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首页> 外文期刊>Biomedical Circuits and Systems, IEEE Transactions on >Scaling of Electrode-Electrolyte Interface Model Parameters In Phosphate Buffered Saline
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Scaling of Electrode-Electrolyte Interface Model Parameters In Phosphate Buffered Saline

机译：磷酸盐缓冲盐水中电极-电解质界面模型参数的缩放

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摘要

We report how the impedance presented by a platinum electrode scales with the concentration of phosphate buffered saline (PBS). We measure the response in various dilutions of PBS with an electrode array as is commonly used in spinal cord stimulator (SCS) implants. We match the parameters of a non-linear electrode-electrolyte interface model to these measurements. We find that the constant phase element of the model scales with approximately the log of concentration, whereas the resistivity is inversely proportional. Using a novel DC measurement technique we show that the onset of Faradaic conduction for a platinum electrode, and thus the safe exposure limit, does not scale with concentration. We compare objective measurements made in saline to those made in the spinal cavity of live sheep. We comment upon the appropriateness of using PBS as a substitute for in-vivo measurements.
机译：我们报告了铂电极呈现的阻抗如何随磷酸盐缓冲盐水（PBS）的浓度缩放。我们用在电极刺激器（SCS）植入物中常用的电极阵列测量PBS各种稀释液中的响应。我们将非线性电极-电解质界面模型的参数与这些测量值进行匹配。我们发现模型的恒定相位元素与浓度的对数成正比，而电阻率则成反比。使用一种新颖的直流测量技术，我们证明铂电极的法拉第传导开始以及安全暴露极限不会随浓度成比例变化。我们将在盐水中进行的客观测量与在活羊的脊髓腔中进行的客观测量进行比较。我们评论使用PBS代替体内测量的适当性。

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