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首页> 外文期刊>Magnetics, IEEE Transactions on >Rotational Drift Spectroscopy for Magnetic Particle Ensembles
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Rotational Drift Spectroscopy for Magnetic Particle Ensembles

机译:磁性粒子组件的旋转漂移光谱

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摘要

Magnetic particles have become a core ingredient for many applications in chemistry, biology, and medical diagnostics, e.g., as a basis for bioanalytical methods or as tracer material for medical imaging. This paper presents a new method called rotational drift spectroscopy (RDS) which uses rotating magnetic fields for measuring the properties of magnetic nanoparticles (MNPs) in liquid suspensions. The RDS signal is based on the nonlinear rotational drift behavior of MNPs in rotating magnetic fields, which is highly dependent on the properties of the MNPs as well as their interaction with the environment. This dependency allows detecting the binding of functionalized MNPs with, e.g., proteins, viruses, or cells with potentially very high sensitivity. This paper presents first experiments demonstrating rotational drift behavior on aggregated magnetic particle ensembles and the corresponding experimental setup.
机译:磁性粒子已成为化学,生物学和医学诊断中许多应用程序的核心成分,例如,作为生物分析方法的基础或医学成像的示踪材料。本文提出了一种称为旋转漂移光谱(RDS)的新方法,该方法使用旋转磁场来测量液体悬浮液中磁性纳米颗粒(MNP)的性能。 RDS信号基于MNP在旋转磁场中的非线性旋转漂移行为,这在很大程度上取决于MNP的特性以及它们与环境的相互作用。这种依赖性使得可以潜在地非常高的灵敏度检测功能化的MNP与例如蛋白质,病毒或细胞的结合。本文提出了第一个实验,展示了在聚集的磁性粒子集合上的旋转漂移行为以及相应的实验设置。

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