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首页> 外文期刊>IEEE Transactions on Magnetics >Micro-Traveling Wave Magnetic Particle Imaging—Sub-Millimeter Resolution With Optimized Tracer LS-008
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Micro-Traveling Wave Magnetic Particle Imaging—Sub-Millimeter Resolution With Optimized Tracer LS-008

机译：微行波磁粉成像—优化示踪剂LS-008的亚毫米分辨率

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摘要

Magnetic particle imaging (MPI) is a novel tomographic imaging method, which allows determining the distribution of superparamagnetic iron-oxide nanoparticles in three dimensions. So far, various MPI systems have been presented with each one emphasizing different scanner features such as large field of view (FOV) or high resolution. For imaging with both high resolution and a large FOV, the optimization and harmonization of hardware parameters as well as tracer material are key prerequisites. The traveling wave MPI (TWMPI) approach uses an array of electromagnets, which can provide a high magnetic field gradient for a high resolution as well as a mouse-sized FOV at the same time. In combination with the tracer LS-008, which is optimized for the MPI technique, a resolution in the sub-millimeter range can be achieved. In this paper, an optimized scanner is presented based on the TWMPI approach featuring a gradient strength up to almost 10 T/m in an FOV with a length of 45 mm providing a high resolution below 500 microns using the optimized LS-008 tracer.
机译：磁性粒子成像（MPI）是一种新颖的层析成像方法，可以确定超顺磁性氧化铁纳米颗粒在三个维度上的分布。到目前为止，已经提出了各种MPI系统，每个系统都强调不同的扫描仪功能，例如大视野（FOV）或高分辨率。对于同时具有高分辨率和大FOV的成像，硬件参数以及示踪剂材料的优化和协调是关键前提。行波MPI（TWMPI）方法使用电磁体阵列，可以提供高磁场梯度以实现高分辨率以及同时具有鼠标大小的FOV。结合针对MPI技术优化的示踪剂LS-008，可以实现亚毫米范围内的分辨率。在本文中，基于TWMPI方法提出了一种优化的扫描仪，该扫描仪使用优化的LS-008示踪剂，在FOV（长度为45 mm）中提供高达近10 T / m的梯度强度，可提供低于500微米的高分辨率。

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