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首页> 外文期刊>IEEE transactions on nanotechnology >Oscillation and Synchronization of Molecular Machines by the Diffusion of Inhibitory Molecules
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Oscillation and Synchronization of Molecular Machines by the Diffusion of Inhibitory Molecules

机译：抑制性分子扩散引起的分子机器的振荡与同步

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The systems of distributed molecular machines (i.e., devices with a size in the nano- to micro-scale range) are anticipated to perform nanoscale to microscale precision functions for future medical applications with cells and for manufacturing applications to pattern molecules. In these applications, molecular machines are mobile and distributed about an environment. The molecular machines coordinate to perform system-level functionality. One common form of coordination is synchronization of molecular machines. Since a single molecular machine has limited ability, multiple molecular machines may synchronize to perform some functionality at the same time to produce a larger scale effect. Synchronization may also be required for multiple molecular machines to coordinate a sequential process. This paper focuses on a simple model for oscillation by molecular machines which release pulses of inhibitory molecules. The inhibitory molecules diffuse and cause synchronization of pulses. Analysis was performed to determine how the number of oscillators, distance between oscillators, and noise of measured concentration impacted the period of oscillation and phase difference among molecular machines.
机译：预期分布式分子机器的系统（即，尺寸在纳米至微米范围内的设备）将执行纳米级至微米级的精确功能，以用于未来的细胞医学应用以及用于图案化分子的制造应用。在这些应用中，分子机器是可移动的并且围绕环境分布。分子机器进行协调以执行系统级功能。协调的一种常见形式是分子机器的同步。由于单个分子机器的功能有限，因此多个分子机器可以同步执行某些功能，以同时产生更大的规模效应。多个分子机器也可能需要同步来协调顺序过程。本文着重于一个简单的分子机器振荡模型，该模型释放抑制分子的脉冲。抑制分子扩散并引起脉冲同步。进行分析以确定振荡器的数量，振荡器之间的距离以及所测量浓度的噪声如何影响分子机器之间的振荡周期和相位差。

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