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首页> 外文期刊>IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control >Nonlinear Shear Modulus Estimation With Bi-Axial Motion Registered Local Strain
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Nonlinear Shear Modulus Estimation With Bi-Axial Motion Registered Local Strain

机译：带轴向运动的局部应变的非线性剪切模量估计

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摘要

Nonlinear elasticity imaging provides additional information about tissue behavior that is potentially diagnostic and avoids errors inherent in applying a linear elastic model to tissue under large strains. Nonlinear elasticity imaging is challenging to perform due to the large deformations required to obtain sufficient tissue strain to elicit nonlinear behavior. This work uses a method of axial and lateral displacement tracking to estimate local axial strain with simultaneous measurement of shear modulus at multiple compression levels. By following the change in apparent shear modulus and the stress deduced from the strain maps, we are able to accurately quantify nonlinear shear modulus (NLSM). We have validated our technique with a mechanical NLSM measurement system. Our results demonstrate that 2-D tracking provides more consistent NLSM estimates than those obtained by 1-D (axial) tracking alone, especially where lateral motion is significant. The elastographic contrast-to-noise ratio in heterogeneous phantoms was 12.5%-60% higher using our method than that of 1-D tracking. Our method is less susceptible to mechanical variations, with deviations in mean elastic values of 2%-4% versus 5%-37% for 1-D tracking.
机译：非线性弹性成像可提供有关组织行为的其他信息，这些信息可以进行诊断，并避免在大应变下将线性弹性模型应用于组织时固有的错误。由于需要足够大的变形以获得足够的组织应变来引发非线性行为，因此非线性弹性成像具有挑战性。这项工作使用轴向和横向位移跟踪的方法来估计局部轴向应变，同时测量多个压缩水平下的剪切模量。通过遵循表观剪切模量和从应变图得出的应力的变化，我们能够准确地量化非线性剪切模量（NLSM）。我们已经通过机械NLSM测量系统验证了我们的技术。我们的结果表明，与仅通过一维（轴向）跟踪获得的结果相比，二维跟踪可提供更一致的NLSM估计，尤其是在横向运动明显的地方。使用我们的方法，异质体模中的弹性成像对比度与噪声之比比一维跟踪高12.5％-60％。我们的方法不太容易受到机械变化的影响，平均弹性值的偏差为2％-4％，而一维跟踪的偏差为5％-37％。

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