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Design of HIFU Transducers for Generating Specified Nonlinear Ultrasound Fields

机译:产生特定非线性超声场的HIFU传感器设计

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Various clinical applications of high-intensity focused ultrasound have different requirements for the pressure levels and degree of nonlinear waveform distortion at the focus. The goal of this paper is to determine transducer design parameters that produce either a specified shock amplitude in the focal waveform or specified peak pressures while still maintaining quasi-linear conditions at the focus. Multiparametric nonlinear modeling based on the Khokhlov–Zabolotskaya–Kuznetsov (KZK) equation with an equivalent source boundary condition was employed. Peak pressures, shock amplitudes at the focus, and corresponding source outputs were determined for different transducer geometries and levels of nonlinear distortion. The results are presented in terms of the parameters of an equivalent single-element spherically shaped transducer. The accuracy of the method and its applicability to cases of strongly focused transducers were validated by comparing the KZK modeling data with measurements and nonlinear full diffraction simulations for a single-element source and arrays with 7 and 256 elements. The results provide look-up data for evaluating nonlinear distortions at the focus of existing therapeutic systems as well as for guiding the design of new transducers that generate specified nonlinear fields.
机译:高强度聚焦超声的各种临床应用对聚焦点的压力水平和非线性波形畸变程度有不同的要求。本文的目的是确定可以在聚焦波形中产生指定冲击振幅或峰值压力的换能器设计参数,同时仍保持准线性条件在焦点上。采用基于Khokhlov–Zabolotskaya–Kuznetsov(KZK)方程的等参非线性模型,并具有等效源边界条件。针对不同的传感器几何形状和非线性失真水平,确定了峰值压力,焦点处的冲击幅度以及相应的源输出。结果以等效单元素球形换能器的参数表示。通过将KZK建模数据与单元素源和7个和256个元素的阵列的测量值和非线性全衍射模拟进行比较,验证了该方法的准确性及其在强聚焦换能器中的适用性。结果提供了查找数据,以评估现有治疗系统关注的非线性畸变,并指导产生特定非线性场的新型换能器的设计。

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