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2-D arterial wall motion imaging using ultrafast ultrasound and transverse oscillations

机译:使用超快超声和横向振荡的二维动脉壁运动成像

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摘要

Ultrafast ultrasound is a promising imaging modality that enabled, inter alia, the development of pulse wave imaging and the local velocity estimation of the so-called pulse wave for a quantitative evaluation of arterial stiffness. However, this technique only focuses on the propagation of the axial displacement of the artery wall, and most techniques are not specific to the intima???media complex and do not take into account the longitudinal motion of this complex. Within this perspective, this paper presents a study of two-dimensional tissue motion estimation in ultrafast imaging combining transverse oscillations, which can improve motion estimation in the transverse direction, i.e., perpendicular to the beam axis, and a phase-based motion estimation. First, the method was validated in simulation. Two-dimensional motion, inspired from a real data set acquired on a human carotid artery, was applied to a numerical phantom to produce a simulation data set. The estimated motion showed axial and lateral mean errors of 4.2 ?? 3.4 μm and 9.9 ?? 7.9 μm, respectively. Afterward, experimental results were obtained on three artery phantoms with different wall stiffnesses. In this study, the vessel phantoms did not contain a pure longitudinal displacement. The longitudinal displacements were induced by the axial force produced by the wall???s axial dilatation. This paper shows that the approach presented is able to perform 2-D tissue motion estimation very accurately even if the displacement values are very small and even in the lateral direction, making it possible to estimate the pulse wave velocity in both the axial and longitudinal directions. This demonstrates the method???s potential to estimate the velocity of purely longitudinal waves propagating in the longitudinal direction. Finally, the stiffnesses of the three vessel phantom walls investigated were estimated with an average relative error of 2.2%.
机译:超快速超声是一种有前途的成像方式,尤其可以实现脉搏波成像的发展和所谓脉搏波的局部速度估计,以定量评估动脉僵硬度。然而,该技术仅集中在动脉壁的轴向位移的传播上,并且大多数技术并非专门针对内膜介质复合物,并且没有考虑该复合物的纵向运动。从这个角度出发,本文提出了结合横向振荡的超快成像中二维组织运动估计的研究,该方法可以改善横向方向(即垂直于光束轴的方向)的运动估计以及基于相位的运动估计。首先,该方法在仿真中得到了验证。二维运动是从在人的颈动脉上获取的真实数据集启发而来的,将其应用于数字体模以生成模拟数据集。估计的运动显示轴向和横向平均误差为4.2? 3.4μm和9.9 ??分别为7.9μm。之后,获得了三种具有不同壁刚度的动脉体模的实验结果。在这项研究中,血管模型不包含纯纵向位移。纵向位移是由壁的轴向膨胀所产生的轴向力引起的。本文表明,即使位移值很小,甚至在横向方向上,提出的方法也能够非常精确地执行二维组织运动估计,从而可以在轴向和纵向方向上估计脉搏波速度。这证明了该方法的潜力,它可以估计沿纵向传播的纯纵向波的速度。最后,估计的三个血管模型壁的刚度估计为2.2%的平均相对误差。

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