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The acoustic field in biomedical tissue with midscale inhomogeneities

机译:具有中等尺度不均匀性的生物医学组织中的声场

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Biomedical ultrasound is often used for investigations within and close to tissue inhomogeneities, such as lesions and plaques, that are midsized compared with the ultrasound wavelength. The scaled wavenumber is typically in the range 1 to 100. Even with small (less than 10%) sound speed variations, such objects are associated with very complicated diffractive field magnitude modulations. The corresponding phase modulations are much more regular, and this observation is the basis for the method described in this paper. The acoustic field can be expressed in terms of a scattering integral. For biomedical parameters, calculations with the widely used Born approximation give accurate results in only very limited circumstances. In this paper we demonstrate the importance of the initial phase estimate, and introduce the Phase Corrected Scattering Integral (PCSI) method. We show that remarkably accurate results for the acoustic field can be obtained from a single evaluation of the scattering integral if this incorporates an initial estimate of the phase modulation imposed by the inhomogeneity. A simple ray model can be used to find the phase correction. The PCSI method deals very effectively with scattering due to small changes in sound speed and irregular geometry, both characteristic of biomedical problems.
机译:生物医学超声通常用于与超声波长相比中等大小的组织不均匀性(例如病变和斑块)内部和附近的检查。缩放后的波数通常在1到100的范围内。即使声速变化很小(小于10%),此类对象也会与非常复杂的衍射场幅度调制相关联。相应的相位调制更加规则,这一观察结果是本文所述方法的基础。声场可以用散射积分表示。对于生物医学参数,仅在非常有限的情况下,使用广泛使用的Born近似进行的计算才能得出准确的结果。在本文中,我们演示了初始相位估计的重要性,并介绍了相位校正散射积分(PCSI)方法。我们表明,如果对散射积分进行单次评估,并结合由不均匀性引起的相位调制的初始估计,就可以从声学积分中获得非常准确的结果。可以使用简单的射线模型来找到相位校正。由于声速的微小变化和不规则的几何形状,PCSI方法非常有效地处理了散射,这都是生物医学问题的特征。

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