• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control >High-frame rate, full-view myocardial elastography with automated contour tracking in murine left ventricles in vivo [correspondence]
【24h】

High-frame rate, full-view myocardial elastography with automated contour tracking in murine left ventricles in vivo [correspondence]

机译：高帧率，全视图心肌弹性成像和体内小鼠左心室自动轮廓跟踪[对应]

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Myocardial elastography is a novel method for noninvasively assessing regional myocardial function, with the advantages of high resolution and high precision. The purpose in this paper was to isolate the left ventricle from other structures for better displacement and strain visualization. Using a high-resolution (30 MHz) ultrasound system and a retrospective electrocardiogram (ECG)-gating technique, an extremely high frame rate (up to 8 kHz) was previously shown achievable for full-view (12-mm times 12-mm) myocardial elastography in the murine left ventricle. In vivo experiments were performed in anesthetized normal and infarcted mice [one day after left anterior descending (LAD) coronary artery ligation]. Radio frequency (RF) signals of the left ventricle (LV) in the long-axis view and the associated ECG were simultaneously acquired, with the ECG allowing gating of the RF signals. Incremental axial displacement of the myocardium was estimated using a one-dimensional (1-D) cross-correlation function. The cumulative displacement and strain then were calculated from the incremental displacement. In this paper, after manual selection of 40-50 points along the endo-and epicardial borders in the first frame of the cine-loop, myocardial contour was automatically tracked across the entire LV throughout a full cardiac cycle, which correctly determined the region of interest (ROI) for better interpretation. The cine-loop of the cumulative displacement and strain in one cardiac cycle, in both the normal and infarcted cases, showed that motion and deformation in the infarcted myocardium were significantly reduced, and that the infarcted region underwent thinning, rather than thickening, during systole. High precision of the displacement estimation, due to high frequency (30 MHz) and high frame rate (up to 8 kHz) available with this system, allowed for automated tracking of a manually-initialized myocardial contour over an entire cardiac cycle. High frame rate, full-view myoca-rdial elastography with automated contour tracking could provide regional strain information of the LV throughout an entire cardiac cycle, and characterize normal as well as detect abnormal myocardial function, such as an infarction. The method of automated contour tracking can further enhance the capability of the elastographic technique with minimal user intervention while providing accurate functional information for the detection of disease throughout the entire cardiac cycle.
机译：心肌弹性成像技术是一种无创评估局部心肌功能的新方法，具有高分辨率和高精度的优点。本文的目的是将左心室与其他结构隔离开，以便更好地观察位移和应变。使用高分辨率（30 MHz）超声系统和回顾性心电图（ECG）门控技术，先前显示了全视角（12毫米乘以12毫米）可实现的极高帧频（高达8 kHz）鼠左心室的心肌弹性成像。在麻醉的正常和梗塞的小鼠中进行体内实验[左前降支（LAD）冠状动脉结扎后一天]。长轴视图中左心室（LV）的射频（RF）信号和相关的ECG同时获得，而ECG允许门控RF信号。使用一维（1-D）互相关函数估算心肌的增量轴向位移。然后根据增量位移计算出累积位移和应变。在本文中，在沿电影环路第一帧的内膜和心外膜边界手动选择40-50个点后，在整个心动周期中自动跟踪整个LV的心肌轮廓，从而正确确定了兴趣（ROI）以获得更好的解释。在正常和梗塞情况下，一个心动周期中累积位移和应变的电影环表明，梗塞心肌的运动和变形显着减少，并且在收缩期，梗塞区域变薄而不是变厚。由于该系统具有高频率（30 MHz）和高帧频（高达8 kHz），因此位移估计的精度很高，从而可以在整个心动周期内自动跟踪手动初始化的心肌轮廓。高帧率，具有自动轮廓跟踪功能的全视野心肌弹性成像可以在整个心动周期中提供左心室的局部应变信息，并表征正常以及检测异常的心肌功能，例如梗塞。自动轮廓跟踪的方法可以用最少的用户干预来进一步增强弹性成像技术的功能，同时为整个心动周期的疾病检测提供准确的功能信息。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号