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Characterization of trabecular bone using the backscattered spectral centroid shift

机译:使用后向散射光谱质心位移表征小梁骨

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Ultrasonic attenuation in bone in vivo is generally measured using a through-transmission method at the calcaneus. Although attenuation in calcaneus has been demonstrated to be a useful predictor for osteoporotic fracture risk, measurements at other clinically important sites, such as hip and spine, could potentially contain additional useful diagnostic information. Through-transmission measurements may not be feasible at these sites due to complex bone shapes and the increased amount of intervening soft tissue. Centroid shift from the backscattered signal is an index of attenuation slope and has been used previously to characterize soft tissues. In this paper, centroid shift from signals backscattered from 30 trabecular bone samples in vitro were measured. Attenuation slope also was measured using a through-transmission method. The correlation coefficient between centroid shift and attenuation slope was -0.71. The 95% confidence interval was (-0.86, -0.47). These results suggest that the backscattered spectral centroid shift may contain useful diagnostic information potentially applicable to hip and spine.
机译:通常在骨跟骨处使用穿透传输法来测量体内的超声波衰减。尽管已证实跟骨衰减是预测骨质疏松性骨折风险的有用指标,但在其他临床上重要的部位(例如髋部和脊柱)进行的测量可能会包含其他有用的诊断信息。由于复杂的骨骼形状和介入的软组织数量增加,在这些部位进行透射测量可能不可行。来自背向散射信号的质心偏移是衰减斜率的指标,以前已用于表征软组织。在本文中,测量了来自30个小梁骨样本在体外反向散射的信号的质心偏移。衰减斜率也使用透射法测量。质心位移与衰减斜率之间的相关系数为-0.71。 95%的置信区间为(-0.86,-0.47)。这些结果表明,背向散射光谱质心偏移可能包含有用的诊断信息,这些信息可能适用于髋部和脊柱。

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