• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control >Micro-receiver guided transcranial beam steering
【24h】

Micro-receiver guided transcranial beam steering

机译：微型接收器引导的经颅束转向

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A new method for focusing ultrasound energy in brain tissue through the skull is investigated. The procedure is designed for use with a therapeutic transducer array and a small catheter-inserted hydrophone receiver placed in the brain to guide the array's focus. When performed at high-intensity, a focal intensity on the order of several hundred watts per centimeter-squared is achieved, and cells within a target volume are destroyed. The present study tests the feasibility and range of the method using an ex vivo human skull. Acoustic phase information is obtained from the stationary receiver and used to electrically shift the beam to new locations as well as correct for aberrations due to the skull. The method is applied to a 104-element 1.1 MHz array and a 120-element 0.81 MHz array. Using these array configurations, it is determined that the method can reconstruct and steer a focus over a distance of 50 mm. Application of this minimally invasive technique for ultrasound brain therapy and surgery also is investigated in vitro with a 64-element 0.664 MHz hemisphere array designed for transskull surgery. Tissue is placed inside of a skull and a catheter-inserted receiver is inserted into the tissue. A focus intense enough to coagulate the tissue is achieved at a predetermined location 10 mm from the receiver, the maximum distance that this large element array can electronically steer the focus.
机译：研究了一种通过颅骨聚焦超声能量在脑组织中的新方法。该程序设计用于治疗性换能器阵列和放置在大脑中的小型导管插入水听器，以指导阵列的聚焦。当以高强度执行时，可以获得每平方厘米数百瓦的聚焦强度，并且破坏了目标体积内的细胞。本研究测试了使用离体人类头骨的方法的可行性和范围。声相信息是从固定接收器获得的，用于将光束电移动到新的位置，并校正由于头骨引起的像差。该方法适用于104个元素的1.1 MHz阵列和120个元素的0.81 MHz阵列。使用这些阵列配置，可以确定该方法可以在50 mm的距离上重建和控制焦点。还使用为跨颅手术设计的64元素0.664 MHz半球阵列在体外研究了这种微创技术在超声脑部治疗和外科手术中的应用。将组织放置在颅骨内部，将插入导管的接收器插入组织中。在距接收器10毫米的预定位置上获得了足以凝结组织的足够强度的聚焦，该最大距离是该大型元件阵列可以电子操纵聚焦的最大距离。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号