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Decorrelation-based blood flow velocity estimation: effect of spread of flow velocity, linear flow velocity gradients, and parabolic flow

机译:基于解相关的血流速度估计:血流速度,线性血流速度梯度和抛物线血流的影响

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摘要

In recent years, a new method to measure transverse blood flow, based on the decorrelation of the radio frequency (RF) signals has been developed. In this paper, we investigated the influence of nonuniform flow on the velocity estimation. The decorrelation characteristics of transverse blood flow using an intravascular ultrasound (IVUS) array catheter are studied by means of computer modeling. Blood was simulated as a collection of randomly located point scatterers; moving this scattering medium transversally across the acoustical beam represented flow. First-order statistics were evaluated, and the signal-to-noise ratio from the signals were measured. The correlation coefficient method was used to present the results. Three velocity profiles were simulated: random spread of blood-flow velocity, linear blood-flow velocity gradient, and parabolic blood-flow. Radio frequency and envelope signals were used to calculate the decorrelation pattern. The results were compared to the mean decorrelation pattern for plug blood-flow. The RF signals decorrelation patterns were in good agreement with those obtained for plug blood flow. Envelope decorrelation patterns show a close agreement with the one for plug blood flow. For axial blood flow, there is a discrepancy between decorrelation patterns. The results presented here suggest that the decorrelation properties of an IVUS array catheter for measuring quantitative transverse blood flow probably will not be affected by different transverse blood-flow conditions.
机译:近年来,已经开发了一种基于射频(RF)信号的去相关性来测量横向血流的新方法。在本文中,我们研究了非均匀流动对速度估计的影响。通过计算机建模研究了使用血管内超声(IVUS)阵列导管的横向血流的去相关特性。将血液模拟为随机分布的点散射体的集合;沿声束横向移动该散射介质表示流。评估了一阶统计量,并测量信号的信噪比。相关系数法用来表示结果。模拟了三种速度分布:血流速度的随机分布,线性血流速度梯度和抛物线血流。射频和包络信号用于计算去相关模式。将结果与栓塞血流的平均去相关模式进行比较。射频信号去相关模式与栓塞血流获得的去相关模式非常吻合。包络去相关模式显示与栓塞血流紧密相关。对于轴向血流,去相关模式之间存在差异。此处显示的结果表明,用于测量定量横向血流的IVUS阵列导管的去相关特性可能不会受到不同横向血流条件的影响。

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