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首页> 外文期刊>IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control >Displacement and strain imaging of coronary arteries with intraluminal ultrasound
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Displacement and strain imaging of coronary arteries with intraluminal ultrasound

机译：腔内超声对冠状动脉的位移和应变成像

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Tissue elasticity can be estimated from displacement and strain images acquired under controlled deformation. We extend this approach for coronary arteries, deformed and imaged by an integrated angioplasty balloon and ultrasonic imaging probe. Because the lumen cross section of a severely occluded artery is not circular, we have also developed a technique to perform all motion computations in the reference frame of the lumen's geometric center. This coordinate system is independent of the imaging catheter and consequently referencing to this frame removes artifacts associated with probe motion within the balloon during deformation. Displacements and strains estimated by phase-sensitive correlation-based speckle tracking were used to distinguish arterial plaques in simulated coronary arteries of differing elastic moduli: hard, soft, and homogenous. We have also applied these methods to images of a homogeneous gelatin phantom collected with the integrated probe. The maximum phantom displacement was about 40 pm, and the maximum radial normal strain was about 4% (absolute value). The spatial dependence of these quantities shows good agreement with theoretically predicted values.
机译：可以从在受控变形下获取的位移和应变图像估计组织弹性。我们将这种方法扩展到冠状动脉，通过整合的血管成形术球囊和超声成像探头对畸形和成像进行成像。由于严重阻塞的动脉的内腔横截面不是圆形的，因此我们还开发了一种在内腔几何中心的参考框架中执行所有运动计算的技术。该坐标系独立于成像导管，因此参考该框架可消除与变形期间球囊内探针运动相关的伪影。通过基于相敏相关性斑点跟踪的估计的位移和应变，可以区分具有不同弹性模量（硬，软和均质）的模拟冠状动脉中的动脉斑块。我们还将这些方法应用于使用集成探针采集的均质明胶体模的图像。最大幻像位移约为40 pm，最大径向法向应变约为4％（绝对值）。这些量的空间依赖性与理论预测值显示出良好的一致性。

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