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首页> 外文期刊>IEEE transactions on visualization and computer graphics >Comprehensive Modeling and Visualization of Cardiac Anatomy and Physiology from CT Imaging and Computer Simulations
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Comprehensive Modeling and Visualization of Cardiac Anatomy and Physiology from CT Imaging and Computer Simulations

机译：通过CT成像和计算机模拟对心脏解剖和生理进行综合建模和可视化

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摘要

In clinical cardiology, both anatomy and physiology are needed to diagnose cardiac pathologies. CT imaging and computer simulations provide valuable and complementary data for this purpose. However, it remains challenging to gain useful information from the large amount of high-dimensional diverse data. The current tools are not adequately integrated to visualize anatomic and physiologic data from a complete yet focused perspective. We introduce a new computer-aided diagnosis framework, which allows for comprehensive modeling and visualization of cardiac anatomy and physiology from CT imaging data and computer simulations, with a primary focus on ischemic heart disease. The following visual information is presented: (1) Anatomy from CT imaging: geometric modeling and visualization of cardiac anatomy, including four heart chambers, left and right ventricular outflow tracts, and coronary arteries; (2) Function from CT imaging: motion modeling, strain calculation, and visualization of four heart chambers; (3) Physiology from CT imaging: quantification and visualization of myocardial perfusion and contextual integration with coronary artery anatomy; (4) Physiology from computer simulation: computation and visualization of hemodynamics (e.g., coronary blood velocity, pressure, shear stress, and fluid forces on the vessel wall). Substantially, feedback from cardiologists have confirmed the practical utility of integrating these features for the purpose of computer-aided diagnosis of ischemic heart disease.
机译：在临床心脏病学中，解剖学和生理学都需要诊断心脏病。 CT成像和计算机模拟为此提供了有价值的补充数据。然而，从大量的高维多样化数据中获取有用的信息仍然具有挑战性。当前工具尚未完全集成，无法从一个完整而集中的角度可视化解剖和生理数据。我们引入了一种新的计算机辅助诊断框架，该框架可从CT成像数据和计算机模拟中对心脏解剖结构和生理进行全面建模和可视化，主要侧重于缺血性心脏病。呈现以下视觉信息：（1）CT成像的解剖：心脏解剖的几何建模和可视化，包括四个心腔，左右心室流出道和冠状动脉； （2）CT成像的功能：运动建模，应变计算以及四个心腔的可视化； （3）CT成像的生理学：心肌灌注的定量和可视化以及与冠状动脉解剖结构的背景融合； （4）来自计算机模拟的生理学：血液动力学的计算和可视化（例如冠状动脉血流速度，压力，剪切应力和血管壁上的流体力）。基本上，心脏病专家的反馈已经证实了将这些功能集成到缺血性心脏病的计算机辅助诊断中的实用性。

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    Guanglei Xiong; Peng Sun; Haoyin Zhou; Seongmin Ha; Bríain ó Hartaigh; Quynh A. Truong; James K. Min;

  • 作者单位

    Dalio Institute of Cardiovascular Imaging and Department of Radiology, Weill Cornell Medical College, New York, NY;

    Dalio Institute of Cardiovascular Imaging and Department of Radiology, Weill Cornell Medical College, New York, NY;

    Dalio Institute of Cardiovascular Imaging and Department of Radiology, Weill Cornell Medical College, New York, NY;

    Dalio Institute of Cardiovascular Imaging and Department of Radiology, Weill Cornell Medical College, New York, NY;

    Dalio Institute of Cardiovascular Imaging and Department of Radiology, Weill Cornell Medical College, New York, NY;

    Dalio Institute of Cardiovascular Imaging and Department of Radiology, Weill Cornell Medical College, New York, NY;

    Dalio Institute of Cardiovascular Imaging and Department of Radiology, Weill Cornell Medical College, New York, NY;

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  • 正文语种 eng
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  • 关键词

    Computed tomography; Heart; Arteries; Physiology; Computational modeling; Data visualization;

    机译：计算机体层摄影术;心脏;动脉;生理学;计算模型;数据可视化;

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