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Multi-objective differential evolution-based ensemble method for brain tumour diagnosis

机译:基于多目标差分进化的集成方法在脑肿瘤诊断中的应用

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摘要

Accurate diagnosis of tumour type is a paramount issue in the appropriate treatment of cancer. In this study, a novel multi-step method, recognising benign and malignant tumour slices in real brain computed tomography (CT) images is proposed. First, image reconstruction is conducted for mixed noise removal using 'weighted encoding with sparse non-local regularisation' technique. For the segmentation purpose, support vector machine (SVM) is performed on CT images. Afterwards, 17 features are extracted, among which multiple important features are selected by the genetic algorithm. These selected features are used as the input to the multilayer perceptron neural network, the weighted kernel width SVM and the k-nearest neighbours models in tumour classification phase. Following this, the outcomes of mentioned classifiers are combined by means of multi-objective differential evolution-based ensemble technique, in order to enhance the classification performance indices. The parameters of this weighted linear combination are found by solving an optimisation problem containing precision and recall as the objective functions. The performance of the implemented approach is compared with the experienced radiologist ground truth and some state-of-the-art methods. The results demonstrate that the ensemble technique achieves high classification rates including the accuracy of 98.65%.
机译:在适当治疗癌症中,准确诊断肿瘤类型至关重要。在这项研究中,提出了一种新颖的多步骤方法,该方法可以在真实的计算机断层扫描(CT)图像中识别良性和恶性肿瘤切片。首先,使用“具有稀疏非局部正则化的加权编码”技术对混合噪声进行图像重建。出于分割的目的,对CT图像执行支持向量机(SVM)。然后,提取17个特征,通过遗传算法选择多个重要特征。这些选定的特征用作肿瘤分类阶段中多层感知器神经网络,加权核宽度SVM和k近邻模型的输入。此后,通过基于多目标差分进化的集成技术将上述分类器的结果进行组合,以增强分类性能指标。通过解决包含精度和召回率作为目标函数的优化问题,可以找到此加权线性组合的参数。将已实施方法的性能与经验丰富的放射科医生的地面真实情况和一些最新方法进行比较。结果表明,该集成技术实现了较高的分类率,包括98.65%的准确性。

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