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首页> 外文期刊>Indian Journal of Otolaryngology and Head & Neck Surgery >Rhinocerebral mucormycosis: An analysis of probable mode of spread and its implication in an early diagnosis and treatment
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Rhinocerebral mucormycosis: An analysis of probable mode of spread and its implication in an early diagnosis and treatment

机译：鼻脑毛霉菌病：可能的传播方式分析及其在早期诊断和治疗中的意义

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摘要

The study was done in two parts: 1. Analysis of CT scan findings of 17 cases of mucormycosis to determine paranasal sinus, orbital and intra-cranial involvement. 2. Cadaveric dissections of the ethmoid complex anatomy to correlate the probable mode of spread. Ethmoidal sinus was found to be the most commonly involved. The disease probably appears first here, spreads to orbit through the lamina papyracea and then through the retro-orbital region, intra-cranially. Our aim would be to diagnose the disease at the stage of ethmoid involvement. In immuno-compromised patients, if headache, peri- or retro-orbital pain or blood stained nasal discharge occur; a CT scan of the paranasal sinuses and a nasal endoscopy with biopsy from anterior ethmoids, if this area shows pathology then CT scan must be performed. If this is positive for mucormycosis, surgical debridement of the involved sinuses is to be done and Amphotericin B as intra-venous infusion and treatment of underlying condition is started.
机译：该研究分为两个部分：1.分析17例毛霉菌病的CT扫描结果，以确定鼻旁窦，眼眶和颅内受累情况。 2.筛骨复杂解剖的尸体解剖，以关联可能的传播方式。筛窦被发现是最常见的。该病可能首先出现在这里，然后通过纸莎草层蔓延到眼眶，然后再通过颅内通过眼眶后区域传播。我们的目标是在筛骨筛查阶段诊断疾病​​。在免疫功能低下的患者中，如果出现头痛，眶周或眶后疼痛或鼻腔血染血；鼻旁窦的CT扫描和鼻前筛窦活检的鼻内窥镜检查，如果该区域显示病理，则必须进行CT扫描。如果这对毛霉菌病是阳性的，则要对涉及的鼻窦进行手术清创术，并开始进行静脉输注和治疗基础疾病的两性霉素B。

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