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首页> 外文期刊>Indian Journal of Pediatrics >Zinc in child health and disease
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Zinc in child health and disease

机译：锌与儿童健康和疾病

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摘要

Zinc deficiency is common in children from developing countries due to lack of intake of animal foods, high dietary phytate content, inadequate food intake and increased fecal losses during diarrhea. Zinc has a fundamental role in cellular metabolism, with profound effects on the immune system and the intestinal mucosa. Zinc supplementation has shown significant benefits in prevention and treatment of diarrhea and pneumonia. Routine zinc supplementation given to low birth weight babies for a year has resulted in substantial reduction in mortality. Zinc deficiency may have adverse effects on physical growth and neurodevelopment. WHO Task Force, 2001, and the National task Force of IAP has recommended use of zinc in the treatment of diarrhea. It is also recommended as part of standard case management in persistent diarrhea and in those with severe malnutrition. Further evidence is required for qualifying its use in treatment of other infective diseases like pneumonia and malaria. Improved dietary quality & intake, food fortification and cultivation of zinc dense plants are some ways of mitigating zinc deficiency.
机译：由于缺乏动物性食物摄入，饮食中的植酸含量高，食物摄入不足以及腹泻时粪便流失增加，发展中国家的儿童普遍缺锌。锌在细胞代谢中起着基本作用，对免疫系统和肠粘膜有深远的影响。补充锌在预防和治疗腹泻和肺炎方面显示出显着的益处。低出生体重婴儿一年定期补充锌可大幅降低死亡率。锌缺乏可能对身体发育和神经发育产生不利影响。 WHO 2001年工作队和IAP国家工作队建议使用锌来治疗腹泻。在持续性腹泻和严重营养不良的患者中，也建议将其作为标准病例管理的一部分。需要更多证据来证明其可用于治疗其他传染性疾病，例如肺炎和疟疾。改善饮食质量和摄入量，强化食物和种植锌密植物是缓解锌缺乏症的一些方法。

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