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首页> 外文期刊>Indian Journal of Pediatrics >Intravenous immunoglobulins in severe Guillian-Barre syndrome in childhood
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Intravenous immunoglobulins in severe Guillian-Barre syndrome in childhood

机译:儿童严重格林-巴利综合征的静脉内免疫球蛋白

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Objective : This is a retrospective analysis of 25 children with severe Guillaln-Barre syndrome admitted to our PICU.Method : All children were treated with intravenous immunoglobulins (IVIG) in a dose of 2 g/kg body weight over 2–5 days in addition to supportive and respiratory care. Seventeen children were elective admissions to the PICU whereas 8 children were transferred from other hospitals in a critical condition. Five of 8 of the late referrals died as compared to none of the elective admissions.Result : All 8 of the late referrals required mechanical ventilation as against 3 of the 17 elective admissions. Mean duration of PICU stay in the late referrals was 27 days as compared to 15 days in the elective admissions.Conclusion : The authors concur with previously published reports, that early use of IVIG could reduce the mortality and the need for intubation and mechanical ventilation. Key words Guillain-Barre syndrome - Intravenous immunoglobulins
机译:目的:这是对我院重症监护室(PICU)收治的25例重症吉兰-巴雷综合征患儿的回顾性分析。方法:所有患儿均在2-5天内接受了静脉注射免疫球蛋白(IVIG)治疗,剂量为2 g / kg体重进行支持和呼吸护理。 17名儿童被选为重症监护病房,而8名儿童因病危急而从其他医院转移。 8个迟到的转诊患者中有5人死亡,而没有任何选择性入学的患者死亡。结果:所有8个迟到的转诊患者都需要机械通气,而17个选择性入学的患者中有3人死亡。晚期转诊的PICU平均住院时间为27天,而选择性入院为15天。结论:作者同意先前发表的报告,早期使用IVIG可以降低死亡率,降低插管和机械通气的需要。关键词格林-巴利综合征-静脉免疫球蛋白

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