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Steachol~® is the best natural solution for the primary prevention of cardiovascular disease

机译：Steachol〜®是预防心血管疾病的最佳天然解决方案

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At the world level and according to World Health Organization, cardiovascular diseases remain the leading cause of death. An estimated 17.3 million deaths per year is attributable to cardiovascular diseases, which is equivalent to 30% of global deaths. The high cholesterol level and metabolic syndrome (hypertension, impaired fasting glucose, excessive waist circumference, hyper-triglyceridemia, low HDL-cholesterol rate), are major risk factors for cardiovascular diseases. High levels of LDL (low density lipoprotein)-cholesterol, characteristic of hypercholesterolemia, is a causative factor of atherosclerosis and its complications. Any reduction in LDL-cholesterol is associated with decreased cardiovascular risks: in primary prevention, a reduction in LDL-cholesterol of 26% is associated with a decrease of the coronary relative risk of 31%. Dietary and hygienic measures, though essential often show themselves insufficient and cholesterol lowering treatments are usually implemented. However, some of them, in particular statins, do not lack side effects (myalgia, muscle wasting, loss of memory ...). Besides too high level of LDL-cholesterol, oxidation of the latter also plays an important role in the increase of cardiovascular risks by promoting the process of atherosclerosis. Indeed, during this long process, oxidized LDL-cholesterol accumulates in a pathological way at the level of the internal wall of arteries, seriously disrupting endothelial function (increase of adhesion factors, oxidation of nitrogen monoxide, ...), and eventually form atherosclerotic plaques whose evolution can lead to cardiovascular events.
机译：在世界范围内，据世界卫生组织称，心血管疾病仍然是主要的死亡原因。每年估计有1,730万人死于心血管疾病，相当于全球死亡人数的30％。高胆固醇水平和代谢综合征（高血压，空腹血糖受损，腰围过多，高甘油三酸酯血症，高密度脂蛋白胆固醇率低）是心血管疾病的主要危险因素。高胆固醇血症的特征是高水平的LDL（低密度脂蛋白）胆固醇是动脉粥样硬化及其并发症的病因。 LDL-胆固醇的任何降低均与心血管风险降低有关：在一级预防中，LDL-胆固醇的降低26％与冠状动脉相对危险性降低31％有关。饮食和卫生措施虽然必不可少，但常常显示出自身不足，因此通常采用降低胆固醇的治疗方法。但是，其中一些药物，尤其是他汀类药物并不缺乏副作用（肌痛，肌肉消瘦，记忆力减退...）。除了过高的LDL-胆固醇含量外，后者的氧化作用还通过促进动脉粥样硬化的进程在增加心血管疾病风险中发挥重要作用。实际上，在此漫长的过程中，氧化的LDL-胆固醇以病理方式积聚在动脉内壁水平，严重破坏了内皮功能（粘附因子增加，一氧化氮的氧化……），最终形成动脉粥样硬化斑块的进化会导致心血管事件。

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    《Innovations in food technology》 |2015年第5期|40-41|共2页
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