Evaluation of Potential Skin Irritation Reaction Arising from Polymer Materials of Medical Devices

Colleen Toole

首页> 外文期刊>Inside R & D >Evaluation of Potential Skin Irritation Reaction Arising from Polymer Materials of Medical Devices

【24h】

Evaluation of Potential Skin Irritation Reaction Arising from Polymer Materials of Medical Devices

机译：评价医疗器械聚合物材料引起的潜在皮肤刺激反应

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The Draize skin irritation test has been employed for skin irritation tests for more than a decade. However, its accuracy has never been validated properly. Therefore, the concern about the test's predictivity and reproducibility, animal welfare groups and pressure from European regulatory authorities (e.g., the Cosmetics Directive), have prompted a search for alternative methods for testing safety of the chemicals. Skin irritancy testing is also recommended for all medical devices. The previously used Draize test and the currently employed ex vivo test were validated using pure chemical irritants, not dilute mixtures extracted from medical devices.

机译：Draize皮肤刺激性试验已用于皮肤刺激性试验已有十多年了。但是，其准确性从未得到正确验证。因此，对测试的可预测性和可重复性，动物福利团体以及来自欧洲监管机构（例如化妆品指令）的压力的关注促使人们寻求用于测试化学品安全性的替代方法。还建议对所有医疗设备进行皮肤刺激性测试。以前使用的Draize测试和当前使用的离体测试均使用纯化学刺激物而非从医疗设备中提取的稀释混合物进行了验证。

著录项

来源
《Inside R & D》 |2013年第45期|3-3|共1页
作者
Colleen Toole;
展开▼
作者单位

CeeTox Inc., 4717 Campus Drive, Kalamazoo, MI 49008;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Evaluation of the medical devices benchmark materials in the controlled human patch testing and in the RhE in vitro skin irritation protocol [J] . Kandarova Helena, Bendova Hana, Letasiova Silvia, Toxicology in vitro: an international journal published in association with BIBRA . 2018,第期

机译：评估受控人类贴片测试中的医疗器械基准材料和体外皮肤刺激方案中的基准
2. SkinEthic (TM) RHE for in vitro evaluation of skin irritation of medical device extracts [J] . Pellevoisin Christian, Videau Christelle, Briotet Damien, Toxicology in vitro: an international journal published in association with BIBRA . 2018,第期

机译：瘦（TM）RHE用于医疗器械提取物皮肤刺激的体外评价
3. Round robin study to evaluate the Reconstructed Human Epidermis model as an in vitro skin irritation test for medical devices [J] . Coleman Kelly, De Jong Wim, Hoffmann Sebastian, Toxicology Letters: An International Journal Providing a Forum for Original and Pertinent Contributions in Toxicology Research . 2017,第S1期

机译：循环学习评估重建的人表皮模型作为医疗器械的体外皮肤刺激试验
4. The Irritation Potential and Toxicity of Dental Restorative Materials and Gloves [C] . Emma-Christin Loennroth, Houshang Shahnavaz International conference on ergonomics and safety for global business quality and productivity . 2000

机译：牙科恢复材料和手套的刺激潜力和毒性
5. Assessment of skin absorption and irritation potential of arachidonic acid and glyceryl arachidonate using in vitro diffusion cell techniques. [D] . Eppler, Angela Rae. 2005

机译：使用体外扩散池技术评估花生四烯酸和花生四烯酸甘油酯的皮肤吸收和刺激潜力。
6. Evaluation of the Potential of Collagen from Codfish Skin as a Biomaterial for Biomedical Applications [O] . Ana M. Carvalho, Alexandra P. Marques, Tiago H. Silva, 2018

机译：鳕鱼皮肤中胶原蛋白作为生物医学应用生物材料的潜力评估
7. A dual luciferase assay for evaluation of skin sensitizing potential of medical devices [O] . Elisabeth Mertl, Elisabeth Riegel, Nicole Glück, 2019

机译：一种双荧光素酶测定，用于评估医疗器械的皮肤敏感潜力

Evaluation of Potential Skin Irritation Reaction Arising from Polymer Materials of Medical Devices

摘要

著录项

相似文献

相关主题

期刊订阅