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Evaluation of serum metal profile in relation to biri smoking using ICP-MS

机译:使用ICP-MS评价与biri吸烟有关的血清金属谱

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摘要

The metals intake through tobacco smoking is associated with adverse effects for human health. The present study was aimed to understand the effects of biri smoking on smoker's serum metal profile. Seven metals, cadmium (Cd), nickel (Ni), lead (Pb), chromium (Cr), copper (Cu), iron (Fe) and zinc (Zn), were analysed in serum samples of 20 biri smokers and 20 non-smokers from North India. The Cd, Ni, Pb, Cr and Cu concentrations were higher while Fe and Zn concentrations were lower in smokers compared to non-smokers. The Fe concentrations, the highest among all metals, seemed to be unassociated with the smoking activity. This study indicated that biri smoking is a contributor to the body burden of Cd, Ni, Cu and Cr in the smoker's body. The Cd, Ni, Cu and Fe concentrations are non-significantly associated with the age of smokers at p<0.01 significance level, whereas Pb and Cr concentrations increase and Zn concentrations decrease with the increase in the age of smokers. Serum metal concentrations in the smoker subjects of North India are higher compared to the results of other similar studies. This could be linked to the poor quality of tobacco used in biri. We recommend conducting more detailed and controlled studies in this regard as a smoker is also subjected to other sources of exposure to metals.
机译:吸烟摄入的金属与对人体健康的不利影响有关。本研究旨在了解Biri吸烟对吸烟者血清金属谱的影响。在20名Biri吸烟者和20名非吸烟者的血清样本中分析了7种金属,镉(Cd),镍(Ni),铅(Pb),铬(Cr),铜(Cu),铁(Fe)和锌(Zn)。 -印度北部的烟民。与不吸烟者相比,吸烟者中的Cd,Ni,Pb,Cr和Cu浓度较高,而Fe和Zn浓度较低。铁的浓度是所有金属中最高的,似乎与吸烟活动无关。这项研究表明,biri吸烟是吸烟者体内Cd,Ni,Cu和Cr负担的原因。在显着性水平p <0.01时,Cd,Ni,Cu和Fe的浓度与吸烟者的年龄无显着相关,而随着吸烟者年龄的增加,Pb和Cr的浓度增加而Zn的浓度降低。与其他类似研究的结果相比,印度北部吸烟者中的血清金属浓度更高。这可能与比里使用的烟草质量差有关。我们建议在这方面进行更详细和受控的研究,因为吸烟者还会受到其他金属暴露源的影响。

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