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Prediction of droplet evaporation characteristics of nebuliser based humidifkation and drug delivery devices

机译:基于雾化器的加湿和药物输送装置的液滴蒸发特性的预测

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This study reports on a model for the evaporation of mono-disperse water droplets into air that can be used to aid the design of nebuliser based humidification systems for respiratory treatments and also for predicting droplet size distributions for pulmonary drug delivery devices under either isothermal or adiabatic conditions. The governing equations are developed from the coupled mass and energy balances for the droplets and for the surrounding air. An adjustment to one of these equations allows for the modelling of either isothermal or adiabatic conditions. Additionally, the proposed model allows for the variation of fluid transport and thermodynamic properties during the solution of the governing equations. The model is compared to and validated against an overall mass and energy balance and the literature. Confirmation of the general evaporation characteristics of water droplets evaporating into air is gained from the model results and, its accuracy, usability and applicability are improved over existing models. The proposed model indicates that the droplet evaporation process in humidification devices is largely unaffected by the initial water temperature and also indicates advantages of adiabatic conditions when using cascade impactor technology for droplet sizing.
机译:这项研究报告了一个模型,该模型用于将单分散水滴蒸发到空气中,该模型可用于辅助基于雾化器的加湿系统的设计,以用于呼吸治疗以及预测等温或绝热条件下肺部药物输送装置的液滴尺寸分布。条件。控制方程由液滴和周围空气的质量和能量平衡耦合得出。对这些方程式之一的调整允许对等温或绝热条件进行建模。另外,提出的模型允许在控制方程的求解过程中改变流体的传输和热力学性质。将该模型与整体质量和能量平衡以及相关文献进行比较和验证。从模型结果中确认了蒸发到空气中的水滴的一般蒸发特性,并且与现有模型相比,其准确性,可用性和适用性得到了改善。所提出的模型表明,加湿装置中的液滴蒸发过程在很大程度上不受初始水温的影响,并且还表明了在使用级联冲击器技术进行液滴筛分时的绝热条件的优势。

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