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Investigation on three-dimensional temperature field of human knee considering anatomical structure

机译：考虑解剖结构的人膝三维温度场研究

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摘要

Inappropriate heat and mass transfer is an extremely important factor to cause rheumatics of human knee which however receives few attentions up to now. Understanding the thermal behaviors of pathological knee tissues can help diagnose its pathological status and find out the most efficient therapeutical way, which is hard to access otherwise. This paper is dedicated to develop a theoretical model for characterizing the three-dimensional temperature fields of human knee by taking its real anatomical structure into consideration. Based on the classical Pennes bioheat transfer equation, the temperature fields of normal knees and pathological ones under various thermal conditions were numerically simulated and compared, which would help better understand the disease mechanisms causing trouble for human knee. Meanwhile, a medical infrared image system was adopted to map the surface temperature of human knee which qualitatively verifies the theoretical prediction and its diagnostic value. Further, effects of heating from outside on the knee tissue and interventional hyperthermia based on vessel heating were also evaluated. Potential therapeutical strategies were suggested for the thermal rehabilitation of rheumatic knee in the near future.
机译：不适当的传热和传质是引起人膝风湿病的极其重要的因素，但是到目前为止，这种现象很少受到关注。了解病理性膝关节组织的热行为可以帮助诊断其病理状态并找出最有效的治疗方法，否则该方法将很难获得。本文致力于通过考虑人体真实的解剖结构，开发一种表征人体膝部三维温度场的理论模型。基于经典的Pennes生物传热方程，数值模拟和比较了正常膝盖和病理膝盖在各种热条件下的温度场，从而有助于更好地了解造成人膝盖不适的疾病机理。同时，采用医用红外图像系统对人膝的表面温度作图，定性验证了理论预测及其诊断价值。此外，还评估了外部加热对膝部组织的影响以及基于血管加热的介入热疗。建议在不久的将来对风湿性膝关节进行热修复的潜在治疗策略。

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  • 来源
    《International Journal of Heat and Mass Transfer》 |2011年第10期|p.1851-1860|共10页
  • 作者

    Jian Xiao; Zhi-Zhu He; Yang Yang; Bo-Wei Chen; Zhong-Shan Deng; Jing Liu;

  • 作者单位

    Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China,Institute of High Energy Physics, Chinese Academy of Sciences, Beijing 100190, PR China;

    Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China;

    Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China;

    Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China;

    Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China;

    Key Laboratory of Cryogenics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, PR China,Department of Biomedical Engineering,school of Medicine,Tdinghua University,Beijing 100084,PR China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    bioheat transfer; arthritis; rheumatics; hyperthermia; thermal diagnostics; anatomical structure; simulation;

    机译：生物传热;关节炎;风湿病;体温过高;热诊断;解剖结构;模拟;

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