Concentration enhancement of sample solutes in a sudden expansion microchannel with Joule heating

Zhengwei Ge; Chun Yang; Gongyue Tang

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Concentration enhancement of sample solutes in a sudden expansion microchannel with Joule heating

机译：焦耳热在突然扩展的微通道中提高了样品溶质的浓度

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Microfluidic concentration of sample solutes is achieved by using temperature gradient focusing (TGF) in a microchannel with a step change in cross-section. A mathematical model is developed to describe the complex TGF processes. Scaling analysis is conducted to estimate time scales so as to simplify the proposed mathematical model. Numerical computations are performed to obtain the temperature, velocity and sample concentration distributions which allow us to reveal the insightful TGF mechanisms. Experiments are carried out to study the effects of applied voltage, buffer concentration, and channel size on the TGF of sample solutes in both PSMD/Glass and PDMS/PDMS microdevices. It is found that the focusing location of samples varies with these experimental parameters, and this scenario can be explained using our present numerical model. In addition, the experimental parametric effects are summarized using a dimensionless Joule number that is introduced in this study. The Joule number effect in the PDMS/PDMS microdevice is compared with that in the PDMS/Glass microdevice. A more than 450-fold concentration enhancement is obtained within 75 s in the PDMS/PDMS microdevice. Overall, the numerical simulations are found in reasonable agreement with the experimental results.

机译：样品溶质的微流体浓度是通过在横截面上有阶跃变化的微通道中使用温度梯度聚焦（TGF）来实现的。建立了数学模型来描述复杂的TGF过程。进行尺度分析以估计时间尺度，以简化所提出的数学模型。进行数值计算以获得温度，速度和样品浓度分布，这使我们能够揭示有见地的TGF机制。进行实验以研究施加电压，缓冲液浓度和通道大小对PSMD /玻璃和PDMS / PDMS微型设备中样品溶质的TGF的影响。发现样品的聚焦位置随这些实验参数而变化，这种情况可以用我们目前的数值模型来解释。此外，使用本研究中引入的无量纲焦耳数总结了实验参数效应。将PDMS / PDMS微型设备中的焦耳数效应与PDMS /玻璃微型设备中的焦耳数效应进行了比较。在75秒钟内，PDMS / PDMS微型设备的浓度提高了450倍以上。总的来说，发现数值模拟与实验结果合理吻合。

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来源
《International Journal of Heat and Mass Transfer》 |2010年第14期|2722-2731|共10页
作者
Zhengwei Ge; Chun Yang; Gongyue Tang;
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作者单位

School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore;

School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore;

School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore 639798, Singapore United Test and Assembly Center Ltd., Singapore 554916, Singapore;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);
原文格式 PDF
正文语种 eng
中图分类
关键词
temperature gradient focusing; joule heating; electrokinetic mass transport; microfluidics;

机译：温度梯度聚焦;焦耳加热电动传质;微流体;

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1. Towards high concentration enhancement of microfluidic temperature gradient focusing of sample solutes using combined AC and DC field induced Joule heating [J] . Zhengwei Ge, Wei Wang, Chun Yang Lab on a chip . 2011,第7期

机译：交流和直流电场感应焦耳加热可实现高浓度增强样品溶质的微流体温度梯度聚焦
2. Microfluidic concentration of sample solutes using Joule heating effects under a combined AC and DC electric field [J] . Zhengwei Ge, Liwen Jin, Chun Yang International Journal of Heat and Mass Transfer . 2015,第juna期

机译：在交流和直流电场下，利用焦耳热效应对样品溶质进行微流体浓缩
3. Joule heating and its effects on electrokinetic transport of solutes in rectangular microchannels [J] . Tang GY, Yan DG, Yang C, Sensors and Actuators, A. Physical . 2007,第1a2期

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4. MICROFLUIDIC CONCENTRATION OF SAMPLE SOLUTES USING JOULE HEATING EFFECTS UNDER COMBINED AC AND DC ELECTRIC FIELD [C] . Zhengwei Ge, Chun Yang International conference on nanochannels, microchannels and minichannels;ICNMM2010 . 2011

机译：交流和直流电场作用下焦耳热效应对样品溶液的微流体浓度
5. Joule heating effects on electrokinetic transport in constriction microchannels. [D] . Sridharan, Sriram. 2011

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6. Micro-Flow Visualization of Red Blood Cell-Enhanced Platelet Concentration at Sudden Expansion [O] . RUI ZHAO, JOIE N. MARHEFKA, FANGJUN SHU, -1

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7. Joule heating and buoyancy effects in electro-osmotic peristaltic transport of aqueous nanofluids through a microchannel with complex wave propagation [O] . Dharmendra Tripathi, Ashish Sharma, O. Anwar Bég 2018

机译：焦耳加热和浮力作用在纳米流体水溶液中通过微通道进行复合波传播的微通道

Concentration enhancement of sample solutes in a sudden expansion microchannel with Joule heating

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