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首页> 外文期刊>International Journal of Innovative Computing Information and Control >INVESTIGATION INTO INDICES OF AGING AND SCHIZOPHRENIA USING THE PHOTIC DRIVING RESPONSE
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INVESTIGATION INTO INDICES OF AGING AND SCHIZOPHRENIA USING THE PHOTIC DRIVING RESPONSE

机译：利用光驱动反应调查衰老和精神分裂症的指标

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摘要

In the current study, we quantitatively evaluated aging and schizophrenia using statistical indices reflecting enhancement and suppression at arbitrary frequencies using photic stimulation (PS). This index corresponds to the Z-score, which reflects the distance between two amplitude distributions at an arbitrary frequency at rest and during PS. We measured EEGs from three groups: 50 healthy subjects aged between 20-30, 30 healthy subjects aged 60 and over, and 31 schizophrenia patients aged 60 and over. We obtained frequency characteristics of Z-scores in each group. Prominent characteristics of fundamental and harmonic components that were sensitive to schizophrenia disease and aging were observed at 6, 7 and 10 Hz PS. We then defined two indices to evaluate schizophrenia symptoms and aging: the average of Z-scores at fundamental and all harmonic frequencies except the harmonics in alpha band and gamma band over 30 Hz (Index A), and the subtraction value of the minimum Z-score in alpha band from the average of the Z-scores in gamma band (Index B). The results revealed a significant difference between the older healthy group and the schizophrenia group in Index A, and between the younger and older groups in Index B.
机译：在当前的研究中，我们使用统计指标定量评估衰老和精神分裂症，这些指标反映了使用光刺激（PS）在任意频率下的增强和抑制。该指标对应于Z分数，它反映了静止和PS期间任意频率下两个幅度分布之间的距离。我们从三组中测量了脑电图：50名年龄在20-30岁之间的健康受试者，30名年龄在60岁以上的健康受试者以及31名60岁以上的精神分裂症患者。我们获得了每组Z得分的频率特征。在6、7和10 Hz PS时观察到对精神分裂症和衰老敏感的基波和谐波成分的突出特征。然后，我们定义了两个指数来评估精神分裂症的症状和衰老：基本和所有谐波频率下Z分数的平均值，除了超过30 Hz的alpha波段和gamma波段的谐波（指数A），以及最小Z-从γ波段Z分数的平均值中获得Alpha波段得分（索引B）。结果显示，指数A的老年健康组和精神分裂症组之间以及指数B的年轻和老年组之间存在显着差异。

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