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首页> 外文期刊>International Journal of Production Research >The elementary flux modes of a manufacturing system: a novel approach to explore the relationship of network structure and function
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The elementary flux modes of a manufacturing system: a novel approach to explore the relationship of network structure and function

机译：制造系统的基本通量模式：探索网络结构与功能之间关系的新方法

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摘要

Elementary flux modes (EFMs) are a concept from Systems Biology, where they serve as an indicator of component relevance in metabolic networks. An elementary flux mode is a functionally relevant, non-decomposable path through a given network. In this paper, we apply elementary flux mode analysis to manufacturing systems, with the aim of using the number of EFMs as a predictor for resource significance in the manufacturing system. For this, we formulate a network representation of a manufacturing process, which allows us to define the manufacturing equivalent of a stoichiometric matrix to draw an analogy between metabolic and manufacturing systems. This, in turn, allows the computation of EFMs, which we conduct in a case-study for a real manufacturing system. We further show that the change of EFMs under resource breakdown is a good indicator of the average order lateness in the manufacturing system. In this way, EFMs provide insight into the relationship of network structure and function in manufacturing.
机译：基本通量模式（EFM）是来自System Biology的概念，在该网络中，它们可作为代谢网络中组分相关性的指标。基本通量模式是通过给定网络的功能相关且不可分解的路径。在本文中，我们将基本通量模式分析应用于制造系统，目的是使用EFM的数量作为制造系统中资源重要性的预测指标。为此，我们制定了制造过程的网络表示形式，这使我们能够定义化学计量矩阵的制造当量以在代谢系统和制造系统之间进行类比。反过来，这允许进行EFM的计算，我们将在一个实际制造系统的案例研究中进行该计算。我们进一步表明，资源分解下的EFM的变化是制造系统中平均订单延迟的良好指标。通过这种方式，EFM可以洞察制造中网络结构和功能之间的关系。

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