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The relationship between optical coherence tomography patterns, angiographic parameters and visual acuity in age-related macular degeneration

机译:年龄相关性黄斑变性的光学相干断层扫描模式,血管造影参数与视敏度之间的关系

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摘要

To assess the relationships between visual acuity (VA), fluorescein angiographic parameters and optical coherence tomography (OCT) patterns in exudative age-related macular degeneration (AMD). Fifty eyes with confirmed diagnosis of new exudative AMD who underwent fluorescein angiography (FA) and OCT evaluation were reviewed retrospectively. The greatest linear diameter of lesion (GLD) by FA and central foveal thickness (CFT) by OCT were measured. The OCT scans were evaluated for the presence of diffuse retinal thickening (D), cystic spaces (C), subretinal fluid (S) and pigment epithelial detachment (P) and five OCT patterns were detected (D + S; C; C + S; P + C + S; P + D + S). Angiographic classification of choroidal neovascularizations was performed. Correlations were statistically significant for VA and CFT in all patients whereas VA and GLD correlation was statistically significant only in predominantly classic and minimal classic lesions. The lowest VA values were detected in patients with COCT pattern and/or predominantly classic lesion type by FA. The OCT and FA findings when evaluated simultaneously may provide information regarding visual function in AMD.
机译:评估渗出性年龄相关性黄斑变性(AMD)中的视敏度(VA),荧光素血管造影参数和光学相干断层扫描(OCT)模式之间的关系。回顾性分析了50例经确诊为新渗出性AMD的患者,这些患者接受了荧光素血管造影(FA)和OCT评估。测量了FA的最大病变线直径(GLD)和OCT的最大中央凹厚度(CFT)。评估OCT扫描是否存在弥漫性视网膜增厚(D),囊性间隙(C),视网膜下液(S)和色素上皮脱离(P),并检测到五种OCT模式(D + S; C; C + S ; P + C + S; P + D + S)。脉络膜新生血管的血管造影分类。在所有患者中,VA和CFT的相关性具有统计学意义,而VA和GLD的相关性仅在主要经典和最小经典病变中具有统计学意义。通过FA,在具有COCT模式和/或主要是经典病变类型的患者中检测到最低VA值。当同时评估OCT和FA时,可能会提供有关AMD视觉功能的信息。

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