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Clinal distribution of human genomic diversity across the Netherlands despite archaeological evidence for genetic discontinuities in Dutch population history

机译:尽管有考古证据证明荷兰人口历史中的遗传不连续性,但人类基因组多样性在整个荷兰的临床分布

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Background The presence of a southeast to northwest gradient across Europe in human genetic diversity is a well-established observation and has recently been confirmed by genome-wide single nucleotide polymorphism (SNP) data. This pattern is traditionally explained by major prehistoric human migration events in Palaeolithic and Neolithic times. Here, we investigate whether (similar) spatial patterns in human genomic diversity also occur on a micro-geographic scale within Europe, such as in the Netherlands, and if so, whether these patterns could also be explained by more recent demographic events, such as those that occurred in Dutch population history.
机译:背景技术在欧洲,人类遗传多样性中存在从东南到西北的梯度变化,这是一个公认的观察结果,最近已被全基因组范围的单核苷酸多态性(SNP)数据证实。传统上,这种模式是由旧石器时代和新石器时代的主要史前人类迁徙事件解释的。在这里,我们调查了人类基因组多样性中的(相似)空间模式是否也在欧洲(如荷兰)的微观地理范围内发生,如果是,这些模式是否也可以通过最近的人口统计学事件来解释(例如发生在荷兰人口史上的那些。

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