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Primary cardiac lymphoma: diagnostic tools and treatment challenges

机译:原发性心脏淋巴瘤:诊断工具和治疗挑战

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摘要

Primary cardiac lymphoma (PCL) is a rare malignancy and the optimal treatment strategy remains uncertain. It appears to respond much better to systemic chemotherapy than to surgery and it should be considered in the differential diagnosis of all cardiac tumours before definitive management is undertaken. We report a case of this rare disorder treated successfully with a combination of rituximab and cyclophosphamide, adriamycin, vincristine and prednisolone. The patient developed recurrent unstable ventricular tachycardia (VT) post-chemotherapy secondary to extensive scarring at the tumour site. The tumour as well as the post-treatment scarring is well illustrated by cardiac magnetic resonance imaging highlighting its usefulness in this setting. An implantable cardioverter defibrillator (ICD) was placed. This is only the second case in the literature of PCL to have an ICD placed for recurrent VT. A brief literature review is included.
机译:原发性心脏淋巴瘤(PCL)是一种罕见的恶性肿瘤,最佳治疗策略仍不确定。它对全身化学疗法的反应似乎比对手术的反应要好得多,并且在进行明确的治疗之前,应在所有心脏肿瘤的鉴别诊断中考虑它。我们报告了一例这种罕见疾病的成功治疗,利妥昔单抗和环磷酰胺,阿霉素,长春新碱和泼尼松龙联合治疗。该患者在化疗后因肿瘤部位的广泛瘢痕继发复发性不稳定室性心动过速(VT)。心脏磁共振成像很好地说明了肿瘤以及治疗后的瘢痕形成,突出了其在这种情况下的有用性。放置了植入式心脏复律除颤器(ICD)。这只是PCL文献中第二种为复发性VT放置ICD的情况。包括简短的文献综述。

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