Low-autofluorescence fluoropolymer membrane filters for cell filtration

Kihara Naoto; Kuboyama Daiki; Onoshima Daisuke; Ishikawa Kenji; Tanaka Hiromasa; Ozawa Naoya; Hase Tetsunari; Koguchi Ryohei; Yukawa Hiroshi; Odaka Hidefumi; Hasegawa Yoshinori; Baba Yoshinobu; Hori Masaru

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Low-autofluorescence fluoropolymer membrane filters for cell filtration

机译：低自发荧光的含氟聚合物膜过滤器，用于细胞过滤

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A fluoropolymer membrane filter with through-holes was fabricated by photolithographic patterning and the dry etching method. 380,000 highly packed through-holes, each with a diameter of 7 mu m were able to cover a whole area with a diameter of 13mm. Ethylene tetrafluoroethylene (ETFE) was used as the membrane, which was suitable for the fluorescence detection of rare cells such as circulating tumor cells (CTCs) in human blood. The device fabrication for the size based capture of rare cells in blood such as CTCs is realized in this study. (C) 2018 The Japan Society of Applied Physics.

机译：通过光刻图案化和干蚀刻法来制造具有通孔的含氟聚合物膜过滤器。 380,000个高度填充的通孔（每个直径为7微米）能够覆盖直径13mm的整个区域。乙烯四氟乙烯（ETFE）用作膜，适用于荧光检测人类血液中稀有细胞，例如循环肿瘤细胞（CTC）。这项研究实现了基于尺寸的血液中稀有细胞（如CTC）捕获的设备制造。（C）2018年日本应用物理学会。

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《Japanese journal of applied physics》 |2018年第6s2期|06JF03.1-06JF03.7|共7页
作者
Kihara Naoto; Kuboyama Daiki; Onoshima Daisuke; Ishikawa Kenji; Tanaka Hiromasa; Ozawa Naoya; Hase Tetsunari; Koguchi Ryohei; Yukawa Hiroshi; Odaka Hidefumi; Hasegawa Yoshinori; Baba Yoshinobu; Hori Masaru;
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Asahi Glass Co Ltd, Res Ctr, Yokohama, Kanagawa 2218755, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Asahi Glass Co Ltd, Res Ctr, Yokohama, Kanagawa 2218755, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Asahi Glass Co Ltd, Res Ctr, Yokohama, Kanagawa 2218755, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

Nagoya Univ, Nagoya, Aichi 4648603, Japan;

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机译：从含氟聚合物的膜过滤器中取出的杂质 - 高通量的干扰，未确定分析

Low-autofluorescence fluoropolymer membrane filters for cell filtration

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