...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Japanese journal of applied physics >Implantable optogenetic device with CMOS IC technology for simultaneous optical measurement and stimulation
【24h】

Implantable optogenetic device with CMOS IC technology for simultaneous optical measurement and stimulation

机译：采用CMOS IC技术的可植入光遗传学器件，可同时进行光学测量和刺激

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this study, we have developed an implantable optogenetic device that can measure and stimulate neurons by an optical method based on CMOS IC technology. The device consist of a blue LED array for optically patterned stimulation, a CMOS image sensor for acquiring brain surface image, and eight green LEDs surrounding the CMOS image sensor for illumination. The blue LED array is placed on the CMOS image sensor. We implanted the device in the brain of a genetically modified mouse and successfully demonstrated the stimulation of neurons optically and simultaneously acquire intrinsic optical images of the brain surface using the image sensor. The integrated device can be used for simultaneously measuring and controlling neuronal activities in a living animal, which is important for the artificial control of brain functions. (C) 2017 The Japan Society of Applied Physics
机译：在这项研究中，我们开发了一种可植入光遗传学设备，该设备可以通过基于CMOS IC技术的光学方法测量和刺激神经元。该设备包括用于光学图案化刺激的蓝色LED阵列，用于获取脑表面图像的CMOS图像传感器以及围绕CMOS图像传感器用于照明的八个绿色LED。蓝色LED阵列放置在CMOS图像传感器上。我们将设备植入转基因小鼠的大脑中，并成功地演示了对神经元的光学刺激，并同时使用图像传感器获取了大脑表面的固有光学图像。该集成设备可用于同时测量和控制活体动物的神经元活动，这对于人工控制脑功能很重要。 （C）2017日本应用物理学会

著录项

  • 来源
    《Japanese journal of applied physics》 |2017年第5期|057001.1-057001.7|共7页
  • 作者

    Haruta Makito; Kamiyama Naoya; Nakajima Shun; Motoyama Mayumi; Kawahara Mamiko; Ohta Yasumi; Yamasaki Atsushi; Takehara Hiroaki; Noda Toshihiko; Sasagawa Kiyotaka; Ishikawa Yasuyuki; Tokuda Takashi; Hashimoto Hitoshi; Ohta Jun;

  • 作者单位

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Osaka Univ, Grad Sch Pharmaceut Sci, Lab Mol Neuropharmacol, Suita, Osaka 5650871, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Maebashi Inst Technol, Dept Syst Life Engn, Maebashi, Gumma 371, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

    Osaka Univ, Grad Sch Pharmaceut Sci, Lab Mol Neuropharmacol, Suita, Osaka 5650871, Japan|Osaka Univ, Grad Sch Pharmaceut Sci, IPS Cell based Res Project Brain Neuropharmacol &, Suita, Osaka 5650871, Japan|Chiba Univ, Hamamatsu Univ Sch Med, Kanazawa Univ, Osaka Univ,United Grad Sch Child Dev,Mol Res Ctr, Suita, Osaka 5650871, Japan|Osaka Univ, Fukui Univ, Suita, Osaka 5650871, Japan;

    Nara Inst Sci & Technol, Grad Sch Mat Sci, Nara 630, Japan;

  • 收录信息
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号