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Effects of cavitation-enhanced heating in high-intensity focused ultrasound treatment on shear wave imaging

机译：高强度聚焦超声处理中空化增强加热对剪切波成像的影响

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摘要

High-intensity focused ultrasound (HIFU) therapy is a less invasive method of cancer treatment, in which ultrasound is generated outside the body and focused at the tumor tissue to be thermally coagulated. To enhance the safety, accuracy, and efficiency of HIFU therapy, "multiple-triggered HIFU" has been proposed as a method of cavitation-enhanced heating to shorten treatment time. In this study, we also propose shear wave elastography (SWE) to noninvasively monitor the cavitation-enhanced heating. Results show that the increase in shear wave velocity was observed in the coagulation area, but it was significantly slower when cavitation occurred. This suggests that the cavitation-enhanced heating requires a significantly longer cooling time before the accurate measurement of shear modulus than heating without generating bubbles. (C) 2015 The Japan Society of Applied Physics
机译：高强度聚焦超声（HIFU）治疗是一种侵入性较小的癌症治疗方法，其中超声在体外产生，并聚焦在要热凝的肿瘤组织上。为了提高HIFU治疗的安全性，准确性和效率，已提出“多次触发HIFU”作为空化增强加热的方法，以缩短治疗时间。在这项研究中，我们还提出了剪切波弹性成像（SWE）来无创地监测空化增强加热。结果表明，在凝结区观察到剪切波速度的增加，但是当发生空化时，它的速度明显减慢。这表明，在精确测量剪切模量之前，相比于不产生气泡的加热，提高气蚀的加热需要更长的冷却时间。 （C）2015年日本应用物理学会

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  • 来源
    《Japanese journal of applied physics》 |2015年第7s1期|07HF11.1-07HF11.6|共6页
  • 作者

    Iwasaki Ryosuke; Nagaoka Ryo; Takagi Ryo; Goto Kota; Yoshizawa Shin; Saijo Yoshifumi; Umemura Shin-ichiro;

  • 作者单位

    Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 9808579, Japan.;

    Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 9808579, Japan.;

    Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 9808579, Japan.;

    Tohoku Univ, Grad Sch Engn, Sendai, Miyagi 9808579, Japan.;

    Tohoku Univ, Grad Sch Engn, Sendai, Miyagi 9808579, Japan.;

    Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 9808579, Japan.;

    Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 9808579, Japan.;

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