Development of a time-of-flight mass spectrometer combined with an ion-attachment method for multicomponent gas analysis

Kazunari Takaya; Karin Takahashi; Yuri Deguchi; Yasuhiro Sakai

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Development of a time-of-flight mass spectrometer combined with an ion-attachment method for multicomponent gas analysis

机译：飞行时间质谱仪与离子吸附方法结合用于多组分气体分析的开发

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We developed a new mass spectrometer that can analyse multicomponent gases without fragmentation. This is essentially a time-of-flight (TOF) mass analyser in which the ion attachment method is used for ionisation. The method using this new device is referred to as "time-of-flight analysis in combination with ion-attachment" (TOFIA). TOFIA has the capability to analyse breath gas in about 10min using the radio-frequency (RF) ion-guiding method and a multichannel scaler (MCS). The mass resolution of the trial device was unsatisfactory, but the device can be greatly improved in the future. We successfully analysed exhaled breath gases related to diseases, including ammonia, acetone, and isoprene gases. We expect that the TOFIA device developed in this work will contribute significantly to studies on the relationship between breath gas and health.

机译：我们开发了一种新型质谱仪，可以分析多组分气体而不会产生碎片。这本质上是飞行时间（TOF）质量分析仪，其中使用了离子附着方法进行电离。使用此新设备的方法称为“结合离子附着的飞行时间分析”（TOFIA）。 TOFIA能够使用射频（RF）离子引导方法和多通道定标器（MCS）在大约10分钟内分析呼吸气体。试用设备的质量分辨率不能令人满意，但是将来可以大大改进该设备。我们成功地分析了与疾病有关的呼出气，包括氨气，丙酮和异戊二烯气。我们希望这项工作中开发的TOFIA设备将大大有助于研究呼吸气体与健康之间的关系。

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《Japanese journal of applied physics》 |2014年第10期|106602.1-106602.5|共5页
作者
Kazunari Takaya; Karin Takahashi; Yuri Deguchi; Yasuhiro Sakai;
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Department of Physics, Toho University, Funabashi, Chiba 274-8510, Japan;

Department of Physics, Toho University, Funabashi, Chiba 274-8510, Japan;

Department of Physics, Toho University, Funabashi, Chiba 274-8510, Japan;

Department of Physics, Toho University, Funabashi, Chiba 274-8510, Japan,Research Center for Materials with Integrated Properties, Toho University, Funabashi, Chiba 274-8510, Japan;

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Development of a time-of-flight mass spectrometer combined with an ion-attachment method for multicomponent gas analysis

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