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首页> 外文期刊>Japanese journal of applied physics >Ultrasonic visualization of propagation of myocardial vibration driven by electrical excitation of myocardium of rat in ex vivo experiment
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Ultrasonic visualization of propagation of myocardial vibration driven by electrical excitation of myocardium of rat in ex vivo experiment

机译：体外实验中大鼠心肌电激发驱动的心肌振动传播的超声可视化

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摘要

For the realization of noninvasive and regional myocardial tissue characterization, in the present study, we attempted to elucidate the characteristics of the myocardial response to electrical excitation and its propagation by an ex vivo experiment using a rat left ventricular wall. To visualize such a propagation phenomenon, whose speed is up to several m/s, high-frame-rate ultrasound was used to measure the myocardial vibrations driven by electrical excitation at 72 points along the heart wall with 200 μm intervals at a frame rate of 3472 Hz. The propagation of myocardial vibration was visualized by estimating the delay time between vibration waveforms measured in the reference ultrasonic beam and each ultrasonic beam using the cross-correlation function between the vibration waveforms. From the estimated delay time, we visualized the propagation of myocardial vibration caused by electrical excitation. The propagation speed was estimated to be 2.5 m/s in the entire excised myocardium. It was also estimated to be 1.8 m/s in the middle of the heart wall and 2.2 m/s at the internal and external surfaces of the left-ventricular wall. The results showed that the myocardial vibration driven by electrical excitation could be measured with high-frame-rate ultrasound.
机译：为了实现无创和局部心肌组织特征，在本研究中，我们试图通过使用大鼠左心室壁的体外实验来阐明心肌对电刺激及其传播的反应的特征。为了可视化这种速度高达几m / s的传播现象，高帧频超声被用于以200微米间隔沿心壁以200μm的间隔测量由电激发沿心壁驱动的心肌振动。 3472赫兹通过使用振动波形之间的互相关函数来估计在参考超声束和每个超声束中测量的振动波形之间的延迟时间，从而可视化心肌振动的传播。从估计的延迟时间，我们可以看到由电激发引起的心肌振动的传播。在整个切除的心肌中，传播速度估计为2.5 m / s。估计在心脏壁中央的速度为1.8 m / s，在左心室壁的内部和外部表面的速度为2.2 m / s。结果表明，可以通过高帧频超声测量由电激发驱动的心肌振动。

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  • 来源
    《Japanese journal of applied physics》 |2014年第7s期|07KF25.1-07KF25.7|共7页
  • 作者

    Yuta Fujita; Hideaki Tagashira; Hideyuki Hasegawa; Kohji Fukunaga; Hiroshi Kanai;

  • 作者单位

    Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8579, Japan;

    Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-0845, Japan;

    Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8579, Japan Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan;

    Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-0845, Japan;

    Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8579, Japan;

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