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首页> 外文期刊>Japanese journal of applied physics >Improvement in Accuracy of Ultrasonic Measurement of Transient Change in Viscoelasticity of Radial Arterial Wall Due to Flow-Mediated Dilation by Adaptive Low-Pass Filtering
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Improvement in Accuracy of Ultrasonic Measurement of Transient Change in Viscoelasticity of Radial Arterial Wall Due to Flow-Mediated Dilation by Adaptive Low-Pass Filtering

机译:通过自适应低通滤波提高超声测量Measurement流介导的扩张引起的V动脉壁粘弹性的瞬态变化的准确性

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摘要

In our previous study, the stress-strain relationship of the radial arterial wall was measured and the viscoelasticity of the intima-media region was estimated from the stress-strain relationship. Furthermore, the transient change in viscoelasticity due to flow-mediated dilation (FMD) was estimated by the automated detection of wall boundaries. In the present study, the strain rate was adaptively filtered to improve the accuracy of viscoelasticity estimation by decreasing the high-frequency noise. Additionally, in a basic experiment, this method was validated using a silicone tube (simulating artery). In the basic experiment, the elasticity was estimated with a mean error of 1.2%. The elasticity measured at each beam position was highly reproducible among measurements, whereas there was a slight variation in measured elasticity among beams. Consequently, in in vivo measurements, the normalized mean square error (MSE) was clearly decreased. Additionally, the stress-strain relationship of the radial arterial wall was obtained and the viscoelasticity was estimated accurately. The inner small loop, which corresponds to the negative pressure wave caused by the closure of the aortic valve, can be observed using the adaptive low-pass filtering (LPF). Moreover, the transient changes in these parameters were similar to those in the previous study. These results show the potential of the proposed method for the thorough analysis of the transient change in viscoelasticity due to FMD.
机译:在我们以前的研究中,测量了radial动脉壁的应力-应变关系,并根据应力-应变关系估算了内膜-中膜区域的粘弹性。此外,通过自动检测壁边界估计了由于流动介导的膨胀(FMD)引起的粘弹性的瞬时变化。在本研究中,应变率经过自适应滤波,通过减少高频噪声来提高粘弹性估计的准确性。此外,在基础实验中,使用硅胶管(模拟动脉)验证了该方法。在基础实验中,估计的弹性平均误差为1.2%。在各个测量之间,在每个梁位置测量的弹性可高度再现,而在各梁之间,测量的弹性略有变化。因此,在体内测量中,标准化均方误差(MSE)明显降低了。另外,获得了radial动脉壁的应力-应变关系,并精确地估计了粘弹性。可以使用自适应低通滤波(LPF)来观察内部的小环路,该环路对应于由主动脉瓣关闭引起的负压波。此外,这些参数的瞬态变化与先前的研究相似。这些结果表明了所提出的方法对彻底分析由于FMD引起的粘弹性的瞬态变化的潜力。

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  • 来源
    《Japanese journal of applied physics》 |2012年第7issue2期|p.07GF14.1-07GF14.7|共7页
  • 作者单位

    Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8579, Japan;

    Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8579, Japan;

    Graduate School of Engineering, Tohoku University, Sendai 980-8579, Japan Graduate School of Biomedical Engineering, Tohoku University, Sendai 980-8579, Japan;

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