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Quality improvement of acoustic-resolution photoacoustic imaging of skin vasculature based on practical synthetic-aperture focusing and bandpass filtering

机译:基于实用的合成孔径聚焦和带通滤波的皮肤血管声学分辨率光声成像质量改善

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摘要

We previously developed a compact acoustic-resolution photoacoustic (PA) imaging system with optical fiber-based illumination, by which blood vessels in the rat skin were visualized in vivo. However, there were issues to be improved in the imaging characteristics: blurring in the out-of-focus region of the ultrasound sensor and degraded resolution due to low-frequency components in the PA signals. These are common limitations in acoustic-resolution PA imaging methods. In this study, we attempted to solve these problems by introducing signal processing methods based both on the synthetic-aperture focusing technique, which was applied only to signals in the detection zone of the sensor in the horizontal direction that was determined in advance in a phantom study, and on digital acoustic signal filtering with three specific frequency bands. Ex vivo and in vivo PA imaging of blood vessels in the rat skin and subcutaneous tissue showed the validity of the present signal processing methods. (C) 2018 The Japan Society of Applied Physics
机译:我们以前开发了一种紧凑的声学分辨率光声(PA)成像系统,该系统具有基于光纤的照明,通过该系统可以在体内可视化大鼠皮肤中的血管。但是,存在一些成像特性需要改进的问题:由于PA信号中的低频分量,超声传感器的离焦区域模糊并且分辨率降低。这些是声学分辨率PA成像方法中的常见限制。在这项研究中,我们试图通过引入基于合成孔径聚焦技术的信号处理方法来解决这些问题,该方法仅应用于事先在幻像中确定的水平方向上传感器检测区域中的信号。研究,以及对具有三个特定频带的数字声信号滤波。大鼠皮肤和皮下组织中血管的离体和体内PA成像显示了本信号处理方法的有效性。 (C)2018日本应用物理学会

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