Solution-phase combinatorial synthesis using multicomponent Grignard reagents

Xifu Liang and Mikael Bols

首页> 外文期刊>Journal of the Chemical Society, Perkin Transactions 1 >Solution-phase combinatorial synthesis using multicomponent Grignard reagents

【24h】

Solution-phase combinatorial synthesis using multicomponent Grignard reagents

机译：使用多组分格氏试剂的溶液相组合合成

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Mixtures of up to 8 different alkyl Grignard reagents were prepared from the reaction of alkyl halides withnmagnesium. These multicomponent Grignard reagents were reacted with aldehydes, ketones or esters to producenmixtures of alcohols. Analysis of the product mixtures showed that from the reactions of aldehydes and ketonesnuniform mixtures of products were formed, while from the reaction with esters uniform libraries were onlynobtained after slow addition of the Grignard reagent.

机译：由烷基卤化物与镁的反应制备多达8种不同的烷基格氏试剂的混合物。这些多组分格氏试剂与醛，酮或酯反应生成醇的混合物。产物混合物的分析表明，由醛和酮的反应形成产物的均匀混合物，而与酯的反应仅在缓慢加入格氏试剂后才能得到均匀的库。

著录项

来源
《Journal of the Chemical Society, Perkin Transactions 1》 |2002年第4期|p.503-508|共6页
作者
Xifu Liang and Mikael Bols;
展开▼
作者单位

Department of Chemistry, University of Aarhus, Langelandsgade 140 Aarhus C, DK-8000,Denmark. E-mail: mb@kemi.aau.dk;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Solution-phase combinatorial synthesis using multicomponent Grignard reagents [J] . Liang XF., Bols M. Journal of the Chemical Society, Perkin Transactions 1 . 2002,第4期

机译：使用多组分格氏试剂的溶液相组合合成
2. Two-and Three Dimensional Combinatorial Chemistry from Multicomponent Grignard Reagents [J] . Anne Bulow, Steffen Sinning, Ove Wiborg, Journal of combinatorial chemistry . 2004,第4期

机译：多组分格氏试剂的二维和三维组合化学
3. Polyaromatic Scavenger Reagents (PAHSR): A New Methodology for Rapid Purification in Solution-Phase Combinatorial Synthesis [J] . Joseph S. Warmus, Marianne I. da Silva Organic letters . 2000,第13期

机译：聚芳族清除剂（PAHSR）：溶液相组合合成中快速纯化的新方法
4. Functionalization of porous silicon surfaces by solution-phase reactions with alcohols and grignard reagents [C] . N.Y. Kim, P.E. Laibinis, Materials Research Society Symposium on microcrystalline and nanocrystalline semiconductors . 1999

机译：用醇和格氏试剂溶液相反应的多孔硅表面的官能化
5. Porphyrins: A solvent free synthesis, combinatorial libraries, a solid phase synthesis, and towards a tetra-Grignard reagent. [D] . Gong, Xianchang. 2000

机译：卟啉：无溶剂合成，组合库，固相合成和四格氏试剂。
6. Two Palladium-Catalyzed Domino Reactions from One Set of Substrates/Reagents: Efficient Synthesis of Substituted Indenes and cis-Stilbenoid Hydrocarbons from the Same Internal Alkynes and Hindered Grignard Reagents [O] . Cheng-Guo Dong, Pik Yeung, Qiao-Sheng Hu -1

机译：从一组底物/试剂中进行两个钯催化的多米诺反应：从相同的内部炔烃和受阻的格氏试剂中高效合成取代的茚类和顺式-类苯乙烯烃
7. Two Palladium-Catalyzed Domino Reactions from One Set of Substrates/Reagents: Efficient Synthesis of Substituted Indenes and cis-Stilbenoid Hydrocarbons from the Same Internal Alkynes and Hindered Grignard Reagents [O] . -1

机译：来自一组底物/试剂的两组钯催化的多米诺反应：高效合成来自同一内部炔醇和阻碍格氏试剂的取代茚和顺式 - 斯蒂甲酸碳氢化合物

Solution-phase combinatorial synthesis using multicomponent Grignard reagents

摘要

著录项

相似文献

相关主题

期刊订阅