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首页> 外文期刊>Journal of coatings technology and research >Biocompatibility and antibacterial performance of titanium by surface treatment
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Biocompatibility and antibacterial performance of titanium by surface treatment

机译：表面处理钛的生物相容性和抗菌性能

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摘要

Titanium (Ti) and its alloys are used extensively in implants due to their excellent biocompatibility and mechanical properties. However, Ti-based implant materials have specific complications associated with their applications, such as the loosening of implanted host interface owing to unsatisfactory cell adhesion and the susceptibility of the implants to bacterial infections. Hence, a surface that displays selective biointeractivity, i.e., enhancing beneficial host cell responses but inhibiting pathogenic microbial adhesion, would be highly desirable. This study aims to confer long-lasting antibacterial properties and good biocompatibility on Ti via the microarc oxidation technique. The biocompatibility of the Ti surface was evaluated by cytotoxicity test, and the bacteriostasis rate was evaluated by antibacterial efficacy. The results showed that the implant surface might be nontoxic to cell and its long-lasting antibacterial properties could be significantly improved. These results indicate that such microarc oxidation coatings are expected to have good potential in transcutaneous implant applications.
机译：钛（Ti）及其合金由于其出色的生物相容性和机械性能而广泛用于植入物中。然而，基于钛的植入物材料具有与其应用相关的特定并发症，例如由于不令人满意的细胞粘附和植入物对细菌感染的敏感性而导致植入的宿主界面松动。因此，非常需要显示选择性生物相互作用的表面，即增强有益的宿主细胞反应但抑制病原性微生物粘附的表面。本研究旨在通过微弧氧化技术赋予Ti持久的抗菌性能和良好的生物相容性。通过细胞毒性试验评价Ti表面的生物相容性，并通过抗菌效果评价抑菌率。结果表明，植入物表面可能对细胞无毒，并且其持久的抗菌性能可以得到显着改善。这些结果表明，预期这种微弧氧化涂层在经皮植入物应用中具有良好的潜力。

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