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首页> 外文期刊>The Journal of Alternative and Complementary Medicine >Category I: Original Clinical Research and Category II: Basic Sciences/Review/Case Studies
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Category I: Original Clinical Research and Category II: Basic Sciences/Review/Case Studies

机译：第一类：原始临床研究，第二类：基础科学/综述/案例研究

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Background: Lignans are one of the three main groups ofrnplant compounds classified as phytoestrogens. They havernbeen shown to have health benefits for females throughoutrnthe life span as well as for men in several studies. Enterolactonern(ENL) is a lignan produced in the human gut throughrnfermentation of dietary precursors such as matairesinol andrnhydroxymatairesinol (HMR). Enterolactone is the primaryrncirculating mammalian plant lignan and is used as a biomarkerrnfor plant lignan intake.rnPurpose and hypothesis: This protocol was designed tornprovide a structured environment in which to test the abilityrnof the proprietary dietary supplement, HMRlignan,™ tornalter the levels of mammalian lignans and estrogen metabolitesrnin a population of healthy post-menopausal women.rnAdditionally, frequency of occurrence of hot flashes amongrnthe subjects were tracked/calculated for the study period.rnMaterials and methods: Study design: 8-week controlledrnstudy in 20 menopausal women (diagnosis of natural or surgicalrnmenopause for at least one year; age 50–75 years; BMI u0002rn25 and u0003 35 kg/m2). Study comparing two doses of HMRlignanrn(25 mg/day and 50 mg/day)
机译：背景：木质素是被分类为植物雌激素的植物化合物的三大类之一。在几项研究中，它们被证明对女性一生和男性都具有健康益处。肠内泌酸（ENL）是通过发酵饮食中的前体物质（如马蒂固醇和羟基羟基麦角甾醇（HMR））在人体肠道中产生的木脂素。肠内酯是主要循环的哺乳动物植物木脂素，并被用作植物木脂素摄入的生物标志物。目的和假设：本协议旨在提供结构化的环境，以测试专有膳食补充剂HMRlignanTM破坏哺乳动物木脂素和木脂素水平的能力。绝经后健康女性的体内雌激素代谢物手术绝经至少一年；年龄50-75岁； BMI u0002rn25和u0003 35 kg / m2）。研究比较两种剂量的HMRlignanrn（25 mg /天和50 mg /天）

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