Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics

Roger Bayston Waheed Ashraf and Toni Smith

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Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics

机译：以小菌落变体形式表达的耐甲氧西林金黄色葡萄球菌中的三氯生耐药性：一种逃避对药敏性的新模式

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Objectives Triclosan is in widespread use in domestic, commercial and healthcare settings and is used to reduce methicillin-resistant Staphylococcus aureus (MRSA) load in carriers. Triclosan resistance is uncommon, usually being due to mutation in fabI or overexpression of efflux pumps. This study investigated the ability of triclosan-containing silicone elastomer to kill MRSA adherent to its surface.

机译：目的三氯生在家庭，商业和医疗机构中得到广泛使用，并用于减少携带者的耐甲氧西林金黄色葡萄球菌（MRSA）负载。三氯生耐药性不常见，通常是由于fabI突变或外排泵过表达所致。这项研究调查了含三氯生的硅氧烷弹性体杀死粘附在其表面的MRSA的能力。

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《Journal of Antimicrobial Chemotherapy》 |2007年第5期|848-853|共6页
作者
Roger Bayston Waheed Ashraf and Toni Smith;
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Biomaterials-Related Infection Group Division of Orthopaedic and Accident Surgery School of Medical and Surgical Sciences University Hospitals Nottingham Nottingham NG7 2UH UK;

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1. Comment on: Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics [J] . Paul F. Seaman1 Dietmar Ochs2 and Martin J. Day1 Journal of Antimicrobial Chemotherapy . 2007,第1期

机译：评论：耐甲氧西林的金黄色葡萄球菌中的三氯生耐药性表现为小菌落变体：一种规避防腐剂敏感性的新模式
2. Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics—authors' response [J] . Roger Bayston Waheed Ashraf and Toni Smith Journal of Antimicrobial Chemotherapy . 2007,第1期

机译：以小菌落变体表达的耐甲氧西林金黄色葡萄球菌中的三氯生抗性：规避防腐剂敏感性的新模式-作者的反应
3. Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics. [J] . Bayston R, Ashraf W, Smith T The Journal of Antimicrobial Chemotherapy . 2007,第5期

机译：在耐甲氧西林的金黄色葡萄球菌中表现为小菌落变体的三氯生抗性：一种逃避对药敏性的新模式。
4. Synthesis and Characterization of Biogenic Selenium Nanoparticles with Antimicrobial Properties Made by Staphylococcus aureus, Methicillin-resistant Staphylococcus aureus (MRSA), Escherichia coli and Pseudomonas aeruginosa. [C] . David Medina, Thomas J. Webster Society for Biomaterials annual meeting and exposition . 2018

机译：金黄色葡萄球菌，耐甲氧西林金黄色葡萄球菌（MRSA），大肠杆菌和铜绿假单胞菌制成的具有抗菌特性的生物硒纳米粒子的合成与表征。
5. Effect of Growth Additives on the Growth of Small Colony Variants of Staphylococcus aureus and the Characterization of the Effect of Serum on Phenotypic Switching by Staphylococcus aureus [D] . Alharbi, Fahad Saud. 2021

机译：生长添加剂对金黄色葡萄球菌的小菌落变种生长的影响及血清葡萄球菌表型切换效果的特征
6. Altered Competitive Fitness Antimicrobial Susceptibility and Cellular Morphology in a Triclosan-Induced Small-Colony Variant of Staphylococcus aureus [O] . Sarah Forbes, Joe Latimer, Abdulrahman Bazaid, 2015

机译：三氯生诱导的金黄色葡萄球菌小菌落变异体中竞争适应性抗菌药敏感性和细胞形态的变化
7. Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics [O] . Roger Bayston, Waheed Ashraf, Toni Smith 2007

机译：耐甲氧胞素抗性金黄色葡萄球菌的三胞菌耐药表达为小菌落变体：一种对抗菌剂易感性的疏散模式

Triclosan resistance in methicillin-resistant Staphylococcus aureus expressed as small colony variants: a novel mode of evasion of susceptibility to antiseptics

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