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Localized surface plasmon resonance biosensing by electro-optic modulation with sensitivity and resolution tunability

机译:具有灵敏度和分辨率可调性的电光调制局部表面等离子体共振生物传感

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摘要

The authors demonstrate a localized surface plasmon resonance (LSPR) biosensing technique based on electro-optically modulated attenuated total reflection. Electro-optic effect is utilized to modulate the wavevector of the light for exciting LSPR with the initial wavevector specified by setting the incident angle. The power variation of the attenuated-total-reflected light with the voltage is analyte-dependent and used as indicator to determine analyte concentration. Increasing the voltage has the effects of enlarging the power variation and enhancing the detection resolution. Detection sensitivity depends on the initial light wavevector and can be tuned under various sensing environments for optimal operation. The presented LSPR biosensing possesses the unique features of convenient sensitivity and resolution tunability.
机译:作者展示了一种基于电光调制衰减全反射的局部表面等离子体共振(LSPR)生物传感技术。利用电光效应,通过设置入射角指定的初始波矢,调制用于激发LSPR的光的波矢。衰减后的总反射光的功率随电压的变化取决于分析物,并用作确定分析物浓度的指标。增加电压具有扩大功率变化和提高检测分辨率的效果。检测灵敏度取决于初始光波矢量,可以在各种传感环境下进行调整以实现最佳操作。提出的LSPR生物传感具有便利的灵敏度和分辨率可调性的独特功能。

著录项

  • 来源
    《Journal of Applied Physics》 |2011年第6期|p.998-1002|共5页
  • 作者

    Tzyy-Jiann Wang; Po-Ching Ho;

  • 作者单位

    Institute of Electro-Optical Engineering, National Taipei University of Technology, Taipei 10608, Taiwan;

    Institute of Electro-Optical Engineering, National Taipei University of Technology, Taipei 10608, Taiwan;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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