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首页> 外文期刊>Journal of Applied Physics >Prototype system of noninterferometric phase-contrast computed tomography utilizing medical imaging components
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Prototype system of noninterferometric phase-contrast computed tomography utilizing medical imaging components

机译：使用医学成像组件的非交气管相对造影的原型系统

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摘要

Grating-based x-ray phase-contrast imaging has been demonstrated to provide more information and higher-contrast images for low-Z soft tissues, compared with conventional absorption-based imaging. However, the existing Talbot-Lau phase-contrast devices are operated in either a two- or three-dimensional mode at low energy with a small field of view and long exposure time. This is because of coherence limitations, difficulties in fabricating high aspect ratio gratings, and the slow readout speed of the detector. For preclinical or even clinical applications, a variable x-ray energy, a large field of view, and fast phase-contrast computed tomography (CT) devices are desirable. The noninterferometric grating-based phase-contrast imaging method is a good candidate, as it relaxes requirements on gratings, including grating period and aspect ratio. Based on the noninterferometric imaging principle, we constructed a prototype phase-contrast CT system, at the National Synchrotron Radiation Laboratory of the University of Science and Technology of China, with medical imaging components. This prototype system enables a large field of view and fast phase-contrast CT imaging under medical imaging energies. In this paper, the prototype system and preliminary experimental results are reported, and possible optimization for forthcoming work is also discussed.
机译：已经证明了与常规吸收的成像相比，已经证明了基于栅极的X射线相位对比度成像以提供更高的低Z软组织的信息和更高的对比图像。然而，现有的Talbot-Lau相位对比装置在低能量下以两维模式操作，具有小视野和长曝光时间。这是因为相干限制，制造高纵横比光栅的困难以及检测器的缓慢读出速度。对于临床前或甚至临床应用，可变X射线能量，大型视野和快速相位对比计算机断层扫描（CT）器件是理想的。基于非交感器测定光栅的相位对比度成像方法是良好的候选者，因为它放松了光栅的要求，包括光栅周期和纵横比。基于非交感器测量原理，我们构建了一种原型相位对比CT系统，在中国科技大学的国家同步辐射实验室，具有医学成像组件。该原型系统可以在医学成像能量下实现大视野和快速相位对比CT成像。在本文中，报告了原型系统和初步实验结果，还讨论了即将到来的工作所可能的优化。

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  • 来源
    《Journal of Applied Physics》 |2021年第7期|074901.1-074901.9|共9页
  • 作者

    Z. Wu; W. B. Wei; K. Gao; G. Liu; G. F. Liu; H. X. Sun; J. Jiang; Q. P. Wang; Y. L Lu; Y. C. Tian;

  • 作者单位

    National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China;

    National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China;

    National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China;

    National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China;

    National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China;

    Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of Sciences Suzhou 215163 China;

    Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Ningbo 315201 China;

    National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China;

    National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China;

    National Synchrotron Radiation Laboratory University of Science and Technology of China Hefei 230029 China;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);
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  • 正文语种 eng
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