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From Bayes Through Marginal Utility to Effect Sizes: A Guide to Understanding the Clinical and Statistical Significance of the Results of Autism Research Findings

机译:从贝叶斯到边际效用到效应量:了解自闭症研究结果的临床和统计学意义的指南

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摘要

The objectives of this report are: (a) to trace the theoretical roots of the concept clinical significance that derives from Bayesian thinking, Marginal Utility/Diminishing Returns in Economics, and the “just noticeable difference”, in Psychophysics. These concepts then translated into: Effect Size (ES), strength of agreement, clinical significance, and related concepts, and made possible the development of Power Analysis; (b) to differentiate clinical significance from statistical significance; and (c) to demonstrate the utility of measures of ES and related concepts for enhancing the meaning of Autism research findings. These objectives are accomplished by applying criteria for estimating clinical significance, and related concepts, to a number of areas of autism research.
机译:本报告的目标是:(a)追溯概念临床意义的理论根源,该理论源于贝叶斯思想,经济学中的边际效用/减少收益以及心理物理学中的“明显差异”。这些概念随后被翻译成:效应量(ES),一致性强度,临床意义和相关概念,并使得功率分析的发展成为可能; (b)区分临床意义和统计学意义; (c)展示ES措施和相关概念对增强自闭症研究结果的意义的实用性。这些目的是通过将自闭症研究的标准和相关概念应用于许多自闭症研究领域来实现的。

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