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Brief Report: Significant Differences in Perceived Odor Pleasantness Found in Children with ASD

机译:简要报告:在自闭症儿童中发现的愉悦气味的显着差异

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The aim of our study was to explore possible differences in estimation of odor pleasantness in children with autism spectrum disorders (ASD) compared to controls. Thirty-five patients with Asperger’s syndrome and high functioning autism (mean age 10.8 ± 3.6 years; 31 boys) were compared with 35 healthy control subjects (mean age 10.4 ± 2.4 years; 28 boys). Odor pleasantness was assessed on a 5-point scale using the Sniffin’ Sticks test (Identification part of the test). Patients with ASD, compared to healthy controls, perceived the smell of cinnamon and pineapple as significantly less pleasant (p < 0.05); at the trend level, the same was true of cloves (p < 0.1). The possibility of olfactory dysfunctions as an autism biomarker is discussed.
机译:我们研究的目的是探索与对照组相比,自闭症谱系障碍(ASD)儿童在气味愉悦度评估中的可能差异。将35例阿斯伯格综合症和高自闭症患者(平均年龄10.8±3.6岁;男31岁)与35名健康对照受试者(平均年龄10.4±2.4岁;男28岁)进行了比较。使用Sniffin's Sticks测试(测试的识别部分)以5分制对气味的愉快程度进行了评估。与健康对照组相比,ASD患者感觉到肉桂和菠萝的气味明显较不愉快(p <0.05);在趋势水平上,丁香也是如此(p <0.1)。讨论嗅觉功能障碍作为自闭症生物标志物的可能性。

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