首页> 外文期刊>Journal of Autism and Developmental Disorders >Phenotypic Overlap Between Core Diagnostic Features and Emotional/Behavioral Problems in Preschool Children with Autism Spectrum Disorder
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Phenotypic Overlap Between Core Diagnostic Features and Emotional/Behavioral Problems in Preschool Children with Autism Spectrum Disorder

机译:自闭症谱系学龄前儿童的核心诊断特征与情绪/行为问题之间的表型重叠

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This study examined the phenotypic overlap between core diagnostic features and emotional/behavioral problems in a sample of 335 preschool children with autism spectrum disorder (ASD). Results from principal component analysis (2 components; 49.70% variance explained) suggested substantial phenotypic overlap between core diagnostic features and emotional/behavioral problems. Component I, Emotional Behavioral Repetitive Problems, was independent of the children’s intellectual, adaptive functioning, and structural language abilities. Component II, Social Communication Deficits, was negatively related to the children’s intellectual, adaptive functioning, and structural language abilities. Both components were positively related to parental stress. This exploratory study contributes to our understanding of the ASD phenotype and provides further support for including emotional/behavioral problems as part of the clinical characterization of children with ASD.
机译:这项研究在335名自闭症谱系障碍(ASD)学龄前儿童样本中检验了核心诊断特征与情绪/行为问题之间的表型重叠。主成分分析的结果(2个成分;解释了49.70%的差异)表明核心诊断特征与情绪/行为问题之间存在明显的表型重叠。第一部分,情感行为重复性问题,与孩子的智力,适应功能和结构性语言能力无关。第二部分,社交沟通不足,与儿童的智力,适应功能和结构性语言能力负相关。两种成分都与父母的压力呈正相关。这项探索性研究有助于我们对ASD表型的理解,并为将情绪/行为问题纳入ASD儿童临床特征提供了进一步的支持。

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