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Brief Report: Abnormal Association Between the Thalamus and Brain Size in Asperger’s Disorder

机译:简要报告:在阿斯伯格疾病中,丘脑和大脑大小之间的异常关联

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摘要

The objective of this study was to examine the relationship between thalamic volume and brain size in individuals with Asperger’s disorder (ASP). Volumetric measurements of the thalamus were performed on MRI scans obtained from 12 individuals with ASP (age range: 10–35 years) and 12 healthy controls (age range: 9–33 years). A positive correlation was found between total brain volume and thalamic size in controls, but not in ASP subjects. This occurred in the absence of differences in mean thalamic volumes between the study groups. Findings from this investigation point to an abnormal relationship between the thalamus and its projection areas in ASP and are consistent with similar studies in autism, supporting that these disorders are qualitatively similar and possibly quantitatively different.
机译:这项研究的目的是检查患有阿斯伯格症(ASP)的人的丘脑容量与脑大小之间的关系。丘脑的体积测量是通过MRI扫描获得的,该扫描来自12名ASP患者(年龄范围:10-35岁)和12名健康对照者(年龄范围:9-33岁)。在对照组的总脑容量和丘脑大小之间发现正相关,而在ASP受试者中却没有。这是在研究组之间的平均丘脑体积没有差异的情况下发生的。从这项调查中发现,丘脑与其ASP中的投射区域之间存在异常关系,并且与自闭症的类似研究相一致,支持这些疾病在质量上相似并且在数量上可能不同。

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