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Epidemiological Surveys of Autism and Other Pervasive Developmental Disorders: An Update

机译:自闭症和其他普遍性发育障碍的流行病学调查:更新

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This paper was commissioned by the committee on the Effectiveness of Early Education in Autism of the National Research Council (NRC). It provides a review of epidemiological studies of pervasive developmental disorders (PDD) which updates a previously published article (The epidemiology of autism: a review. Psychological Medicine 1999; 29: 769–786). The design, sample characteristics of 32 surveys published between 1966 and 2001 are described. Recent surveys suggest that the rate for all forms of PDDs are around 30/10,000 but more recent surveys suggest that the estimate might be as high as 60/10,000. The rate for Asperger disorder is not well established, and a conservative figure is 2.5/10,000. Childhood disintegrative disorder is extremely rare with a pooled estimate across studies of 0.2/10,000. A detailed discussion of the possible interpretations of trends over time in prevalence rates is provided. There is evidence that changes in case definition and improved awareness explain much of the upward trend of rates in recent decades. However, available epidemiological surveys do not provide an adequate test of the hypothesis of a changing incidence of PDDs.
机译:本文是由美国国家研究理事会(NRC)的自闭症早期教育有效性委员会委托编写的。它提供了对广泛性发育障碍(PDD)的流行病学研究的综述,该研究更新了先前发表的文章(自闭症的流行病学:review。Psychological Medicine 1999; 29:769-786)。描述了1966年至2001年之间发表的32项调查的设计,样本特征。最近的调查表明,所有形式的PDD的比率约为30 / 10,000,但最新的调查表明,估计的比率可能高达60 / 10,000。阿斯伯格综合症的发病率尚不明确,保守数字为2.5 / 10,000。儿童崩解性疾病极为罕见,研究汇总估计为0.2 / 10,000。提供了关于流行率随时间变化趋势的可能解释的详细讨论。有证据表明,案例定义的变化和意识的提高可以解释近几十年来费率的上升趋势。但是,可用的流行病学调查不能充分证明PDD发生率发生变化的假设。

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