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首页> 外文期刊>Journal of Autism and Developmental Disorders >Prevalence and Patterns of Use of Psychoactive Medicines Among Individuals with Autism in the Autism Society of Ohio
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Prevalence and Patterns of Use of Psychoactive Medicines Among Individuals with Autism in the Autism Society of Ohio

机译：俄亥俄州自闭症协会中自闭症患者中使用精神活性药物的普遍性和使用方式

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摘要

To date, there have been few surveys of psychotropic and antiepileptic drug (AED) prevalence in individuals with autism-spectrum conditions. We surveyed 747 families in the Autism Society of Ohio regarding the use of psychotropic drugs, AEDs, and over-the-counter (OTC) preparations for autism. In all, 417 families (55.8%) replied. A total of 45.6% were taking some form of psychotropic agent (including St. John's wort and melatonin), whereas 11.5% were taking AEDs, and 10.3% took OTC autism preparations. The most common psychotropic agents included antidepressants (21.6%), antipsychotics (14.9%), antihypertensives (12.5%), and stimulants (11.3%). Some 51.6% were prescribed psychotropic drugs or AEDs, and 55.4% took psychotropic drugs, AEDs, or autism supplements. Demographic variables frequently found to be associated with medication use included greater age, more severe autism, more severe intellectual handicap, and housing outside the family home. Whereas there is empirical support for the use of some of these psychotropic agents in autism, others are being prescribed with minimal research support. OTC autism preparations were used in substantial numbers of individuals, despite limited research support and the possibility of toxic effects.
机译：迄今为止，对于自闭症患者的精神和抗癫痫药物（AED）的患病率几乎没有调查。我们调查了俄亥俄州自闭症协会的747个家庭，了解使用精神药物，AED和自闭症非处方药（OTC）的情况。总共有417个家庭（55.8％）答复。总共有45.6％的人服用某种形式的精神药物（包括圣约翰草和褪黑激素），而11.5％的人服用AEDs，10.3％的人服用OTC自闭症制剂。最常见的精神药物包括抗抑郁药（21.6％），抗精神病药（14.9％），抗高血压药（12.5％）和兴奋剂（11.3％）。约有51.6％的人服用了精神药物或AED，而55.4％的人服用了精神药物，AED或自闭症补充剂。经常发现与药物使用相关的人口统计学变量包括年龄较大，自闭症严重，智力障碍更严重以及家庭住所之外。尽管在自闭症中使用其中一些精神药物有经验支持，但在其他研究中却仅需很少的研究支持。尽管研究支持有限且可能产生毒性作用，但仍有大量个人使用OTC自闭症制剂。

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