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首页> 外文期刊>Journal of biomedical optics >Self-referenced, microdegree, optical rotation polarimeter for biomedical applications: an analysis
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Self-referenced, microdegree, optical rotation polarimeter for biomedical applications: an analysis

机译：自参考，微度旋光旋光仪，用于生物医学应用：分析

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摘要

We comprehensively analyze the performance of a type of optical rotation (OR) polarimeter, which has been designed from the outset to fit the special requirements of two major applications: general chiral detection during the separation of optical isomers by high-pressure liquid chromatography systems in the pharmaceutical industry, and monitoring of glucose in the interstitial fluid of diabetics by a fully implanted long-term optical sensor. Both very demanding applications call for an OR polarimeter that can be miniaturized while maintaining high resolution and accuracy in the microdegree range in the face of considerable noise from various sources. These two characteristics-miniature size and immunity to noise-set this polarimeter apart from the traditional OR polarimeters currently in use, which are both bulky and very susceptible to noise. The following detailed analysis demonstrates the advantages of this polarimeter and its potential as an analytic and diagnostic tool.
机译：我们全面分析了一种旋光（OR）旋光仪的性能，该旋光仪从一开始就设计用于满足两种主要应用的特殊要求：高压液相色谱系统中光学异构体分离过程中的常规手性检测。制药业，并通过完全植入的长期光学传感器监测糖尿病患者间质液中的葡萄糖。两种非常苛刻的应用都要求OR旋光仪可以小型化，同时面对来自各种来源的大量噪声，仍可以在微度范围内保持高分辨率和精度。这两个特性-微型尺寸和抗噪声性使该旋光仪与当前使用的传统OR旋光仪不同，后者既笨重又很容易受到噪声的影响。以下详细分析证明了该旋光仪的优势及其作为分析和诊断工具的潜力。

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  • 来源
    《Journal of biomedical optics》 |2016年第7期|071104.1-071104.16|共16页
  • 作者

    Zeev Weissman; Doron Goldberg;

  • 作者单位

    Shenkar College of Engineering and Design, Electrical Engineering Department, 12 Anne Frank Street, Ramat Gan 52526, Israel;

    MIGAL Galilee Research Institute, Medical and Diagnostic Instruments Development, Southern Industrial Zone, Tarshish Street 1, Kiryat Shmona 11016, Israel,Tel Hai College, Faculty of Science and Technology, Upper Galilee, Kiryat Shmona 12209, Israel;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    polarimeters; sensors; biomedical optics;

    机译：旋光仪传感器生物医学光学;

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