Comparison of magnetic resonance imaging-compatible optical detectors for in-magnet tissue spectroscopy: photodiodes versus silicon photomultipliers

Fadi El-Ghussein; Shudong Jiang; Brian W. Pogue; Keith D. Paulsen

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Comparison of magnetic resonance imaging-compatible optical detectors for in-magnet tissue spectroscopy: photodiodes versus silicon photomultipliers

机译：磁共振成像兼容的用于磁性组织光谱的光学探测器的比较：光电二极管与硅光电倍增管

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Tissue spectroscopy inside the magnetic resonance imaging (MRI) system adds a significant value by measuring fast vascular hemoglobin responses or completing spectroscopic identification of diagnostically relevant molecules. Advances in this type of spectroscopy instrumentation have largely focused on fiber coupling into and out of the MRI; however, nonmagnetic detectors can now be placed inside the scanner with signal amplification performed remotely to the high field environment for optimized light detection. In this study, the two possible detector options, such as silicon photodiodes (PD) and silicon photomultipliers (SiPM), were systematically examined for dynamic range and wavelength performance. Results show that PDs offer 10~8 (160 dB) dynamic range with sensitivity down to 1 pW, whereas SiPMs have 10~7 (140 dB) dynamic range and sensitivity down to 10 pW. A second major difference is the spectral sensitivity of the two detectors. Here, wavelengths in the 940 nm range are efficiently captured by PDs (but not SiPMs), likely making them the superior choice for broadband spectroscopy guided by MRI.

机译：磁共振成像（MRI）系统内部的组织光谱学通过测量快速的血管血红蛋白反应或完成对诊断相关分子的光谱学鉴定而增加了可观的价值。这类光谱仪器的进展主要集中在进出MRI的光纤耦合上。但是，现在可以将非磁性检测器放置在扫描仪内部，并在远场环境中远程执行信号放大，以优化光检测。在这项研究中，系统地检查了两个可能的检测器选项，例如硅光电二极管（PD）和硅光电倍增管（SiPM），以了解动态范围和波长性能。结果表明，PD提供10〜8（160 dB）的动态范围，灵敏度低至1 pW，而SiPM具有10〜7（140 dB）的动态范围，灵敏度低至10 pW。第二个主要区别是两个检测器的光谱灵敏度。在这里，PD（而不是SiPM）可以有效捕获940 nm范围内的波长，这很可能使其成为MRI引导的宽带光谱的上乘之选。

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来源
《Journal of biomedical optics》 |2014年第7期|070502.1-070502.3|共3页
作者
Fadi El-Ghussein; Shudong Jiang; Brian W. Pogue; Keith D. Paulsen;
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作者单位

Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, United States;

Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, United States;

Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, United States;

Dartmouth College, Thayer School of Engineering, Hanover, New Hampshire 03755, United States;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
photodetectors; photodetection; magnetic resonance imaging; tomography; medical imaging; spectroscopy;

机译：光电探测器光电检测磁共振成像断层扫描医学影像;光谱学;

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机译：具有等离激元纳米结构的电磁场的操纵：非线性频率混合，光学操纵，硅光电二极管中光电流的增强和抑制以及表面增强光谱。
6. Comparison of magnetic resonance imaging-compatible optical detectors for in-magnet tissue spectroscopy: photodiodes versus silicon photomultipliers [O] . Fadi El-Ghussein, Shudong Jiang, Brian W. Pogue, 2014

机译：磁共振成像兼容的用于磁性组织光谱的光学探测器的比较：光电二极管与硅光电倍增管
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机译：通过信噪比计算比较原子和分子发光光谱中图像器件与光电倍增管探测器的比较。

Comparison of magnetic resonance imaging-compatible optical detectors for in-magnet tissue spectroscopy: photodiodes versus silicon photomultipliers

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